Accurate assessment of TP53 gene status in sporadic tumors and in the germline of individuals at high risk of cancer due to Li–Fraumeni Syndrome (LFS) has important clinical implications for diagnosis, surveillance, and therapy. Genomic data from more than 20,000 cancer genomes provide a wealth of information …

It has been shown that the identification of many foods including vegetables based on flavour cues is often difficult. The effect of providing texture cues in addition to flavour cues on the identification of foods and the effect of providing taste cues only on the identification of foods have not been …

The European Union (EU) and the United States of America (US) are currently negotiating the Transatlantic Trade and Investment Partnership (TTIP). TTIP was launched in 2013. TTIP aims at developing trade rules under investment protection that encompasses arbitration as the method to resolve disputes …

OBJECTIVE: To describe professionals' perceptions of factors that facilitate or hamper the implementation and continuation of a physical activity promotion programme in rehabilitation. DESIGN: This study used a qualitative design. METHODS: Semi-structured interviews (n = 22) were conducted with rehabilitation …

Climate change is a major contributor to the range shifts of several organisms such as plant species. A range is the geographical area where a species can be found and it is possible for plant species to undergo a range shift while still being present in their original one. These plants are called range-expanders. …

OBJECTIVES: to study (i) the prevalence of geriatric conditions in community-dwelling older persons at increased risk of functional decline and (ii) the extent to which older persons recognise comprehensive geriatric assessment (CGA)-identified conditions as relevant problems. METHODS: trained registered …

This thesis is written for Kwekerij De Vesting to determine to what extent a brand of zucchinis can be successful within the Dutch market. Kwekerij De Vesting started to grow zucchinis without any knowledge of the Dutch market in February 2015. This research assesses the needs and desires of the potential …

Company A offers different product types: comfort en luxury. Company A has concluded that the sales of the category luxury is lower than the category comfort. There are different ways concerning online marketing to raise this sale. This research focusses on social media. The primary purpose of this study …

Although assessment practices are commonly part of the physical education (PE) curriculum they may often frustrate rather than support students’ basic needs for autonomy, competence and relatedness. Nevertheless, assessment also provides various promising opportunities to support these basic needs and …

Microfluidic devices have the potential to adopt more accurate physiological conditions of the human intestine through the use of continuous flow and by producing mechanical stress to the cells. This study evaluated the translocation properties of a microfluidic gut-on-chip device in comparison with …