Background A healthy lifestyle is indispensable for the prevention of noncommunicable diseases. However, lifestyle medicine is hampered by time constraints and competing priorities of treating physicians. A dedicated lifestyle front office (LFO) in secondary/tertiary care may provide an important contribution …

Systemic sclerosis (SSc) is an autoimmune disease which is characterized by vasculopathy, tissue fibrosis and activation of the innate and adaptive immune system. Clinical features of the disease consists of skin thickening and internal organ involvement. Due to the heterogeneous nature of the disease …

Background: In addition to medical intervention and counseling, patients with cardiovascular disease (CVD) need to manage their disease and its consequences by themselves in daily life. Objective: The aim of this paper is to describe the development of "Vascular View," a comprehensive, multi-component, …

Dementia and movement disorders. With a greying European society the consequences are already visible with an increase of the prevalence of Alzheimer’s disease and other age-related neurodegenerative and mental disorders. Therefore it is no surprise that the health care cost of brain disease is expected …

Movement disorders and inactivity in dementia. Movement disorders in dementia An interesting article by Ramakers et al in 2007 showed that 5 years prior to the diagnosis of dementia these people significantly more often visited their home physician in contrast with cognitive healthy age matched controls. …

BACKGROUND: Paratonia is a progressive motor problem that is observed in individuals with dementia and is not a well-known phenomenon. This study explores the development and risk factors of paratonia in moderate stage dementia patients. METHODS: A multi-center, longitudinal, one-year follow-up cohort …

Living independently is an important component of quality of life. Cardiovascular diseases are prominent among the chronic conditions that predispose elderly people to functional limitations and disability, which impair quality of life. Insight into factors that play a role in the development process …

OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with …

PURPOSE: Walking ability in general and specifically for lower limb amputees is of major importance for social mobility and ADL independence. Walking determines prosthesis prescription. The aim of this study was to mathematically analyse factors influencing claimed walking distance of lower limb amputees …

Bijna alle mensen met een amputatie hebben in meer of mindere mate last van fantoomverschijnselen. Deze verschijnselen kunnen het dagelijks leven van deze patiënten behoorlijk beïnvloeden. Ondanks het feit dat fantoompijn vaak voorkomt na een amputatie, wordt toch maar een kleine groep patiënten voor …