We zagen een 73-jarige vrouw met een recidiefdepressie en gegeneraliseerde angststoornis. Zeven weken geleden was hiervoor escitalopram door de huisarts gestart. Het middel bleek niet effectief en werd afgebouwd met als doel een ander antidepressivum te starten. Tijdens de afbouw was er sprake van acute …

Climate change with sea level rise cast a spell on spatial planning in The Netherlands, adding further unrest to the control of urban development in the north-east of Noord-Brabant. The pressure from the Randstad is felt already today in this peripheral zone, bound by the Meuse and the precautionary …

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections (LRTI) in infants, and toddlers and vaccines are not yet available. A pediatric RSV vaccine (ChAd155-RSV) is being developed to protect infants against RSV disease. The ChAd155-RSV vaccine consists of a recombinant …

Species responding differently to climate change form ‘transient communities’, communities with constantly changing species composition due to colonization and extinction events. Our goal is to disentangle the mechanisms of response to climate change for terrestrial species in these transient communities …

The aging population faces two conditions that threaten healthy aging: high fat mass (obesity) and low muscle mass and function (sarcopenia). The combination of both—referred to as sarcopenic obesity—synergistically increases the risk of adverse health outcomes. The two conditions often co-occur because …

Application of animal manure to soils results in the introduction of manure-derived bacteria and their antimicrobial resistance genes (ARGs) into soils. ResCap is a novel targeted-metagenomic approach that allows the detection of minority components of the resistome gene pool without the cost-prohibitive …

The current double blind, randomized, placebo-controlled trial with two parallel groups aimed to assess the impact of whey protein supplementation on recovery of muscle function and muscle soreness following eccentric exercise. During a 9-day period, forty recreationally active males received twice daily …

The gig economy is a relatively new, but rapidly evolving, form of employment across the globe and especially amongst younger people in the United Kingdom. Characterised by flexible, individualised and platform-based work, it is fast becoming an attractive means of employment. It is valued for the freedom …

"This publication, leaded by the National University of Singapore School of Design and Environment, presents the research by design results of four consecutive years in four different countries (China, Philippines, Indonesia and Thailand) responding to the current challenge of building more resilient …

Background: Insufficient amounts of physical activity is a risk factor for (recurrent) stroke. People with a stroke or transient ischemic attack (TIA) have a high risk of recurrent stroke and have lower levels of physical activity than their healthy peers. Though several reviews have looked at the effects …