Tumor necrosis factor alpha (TNF-α) and its key role in modulating immune responses has been widely recognized as a therapeutic target for inflammatory and neurodegenerative diseases. Even though inhibition of TNF-α is beneficial for the treatment of certain inflammatory diseases, total neutralization …

Study design Cross-sectional study. Objectives The aims of this study were (1) to validate the two recently developed SCI-specific REE equations; (2) to develop new prediction equations to predict REE in a general population with SCI. Setting University, the Netherlands. Methods Forty-eight community-dwelling …

The objective of this study is to investigate the heart rate (HR) accuracy measured at the wrist with the photoplethysmography (PPG) technique with a Fitbit Charge 2 (Fitbit Inc) in wheelchair users with spinal cord injury, how the activity intensity affects the HR accuracy, and whether this HR accuracy …

STUDY DESIGN: Cross-sectional study. OBJECTIVES: This study: (1) investigated the accuracy of bioelectrical impedance analysis (BIA) and skinfold thickness relative to dual-energy X-ray absorptiometry (DXA) in the assessment of body composition in people with spinal cord injury (SCI), and whether sex …

Purpose/Objective: Most dose-escalation trials in glioblastoma patients integrate the escalated dose throughout the standard course by targeting a specific subvolume. We hypothesize that anatomical changes during irradiation may affect the dose coverage of this subvolume for both proton- and photon-based …

Context: Only 55% of the athletes return to competitive sports after an anterior cruciate ligament (ACL) injury. Athletes younger than 25 years who return to sports have a second injury rate of 23%. There may be a mismatch between rehabilitation contents and the demands an athlete faces after returning …

Cutaneous melanoma is a type of skin cancer that develops from benign melanocytes to one of the most aggressive types of skin tumors in human. In cutaneous melanoma progression, the metastasis phase is the most challenging phase to treat. To enable earlier treatment options, a better understanding of …

Background Skull metastases are rare, they can eventually cause pain, and can invade the brain. Viscum album extracts (VAEs) are used as an adjuvant treatment in cancer. Methods and Results A 68‐year‐old patient with rectal cancer presented with lung metastases, and metastases to multiple bone sites, …

The objective of this study was to determine if a 3-dimensional computer vision automatic locomotion scoring (3D-ALS) method was able to outperform human observers for classifying cows as lame or nonlame and for detecting cows affected and nonaffected by specific type(s) of hoof lesion. Data collection …

In de studie is onderzocht of en in hoeverre de beeldkwaliteit behouden blijft wanneer de scansnelheid van een Total Body Scintigrafie verhoogd wordt van 5 cm/min naar 10 cm/min, al dan niet met gebruik van het softwareprogramma EPP. De beeldkwaliteit is visueel beoordeeld door twee nucleair geneeskundigen …