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Zocht je misschien: does, done?

High- Versus Low-Dose Exercise Therapy for Knee Osteoarthritis

Knoop, Jesper; Dekker, Joost; van der Leeden, Marike; van der Esch, Martin (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen); Ostelo, Raymond W.J.G.

2023-07AlgemeenArtikel

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer

Groen, Wim G.; Naaktgeboren, Willeke R.; van Harten, Wim H.; van Vulpen, Jonna K.; Kool, Nathalie (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); Sonke, Gabe S.; van der Wall, Elsken; Velthuis, Miranda J.; Aaronson, Neil K.; May, Anne M.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker)

INTRODUCTION: An optimal relative dose intensity (RDI) of adjuvant chemotherapy is associated with better survival in patients with breast cancer. Little is known about the role of physical fitness in attaining an adequate RDI in patients with early stage breast cancer. We investigated the association …

2022-04AlgemeenArtikel

Wound infection following implant removal of foot, ankle, lower leg or patella; a protocol for a multicenter randomized controlled trial investigating the (cost-)effectiveness of 2 g of prophylactic cefazolin compared to placebo (WIFI-2 trial)

Sanders, Fay R.K.; Penning, Diederick; Backes, Manouk; Dingemans, Siem A.; van Dieren, Susan; Eskes, Anne M. (Lectoraat Patiënt- En Familieparticipatie In De Klinische Zorg); Goslings, J. Carel; Kloen, Peter; Mathôt, Ron A.A.; Schep, Niels W.L.; Spijkerman, Ingrid J.B.; Schepers, Tim

Background: Elective implant removal (IR) after fracture fixation is one of the most common procedures within (orthopedic) trauma surgery. The rate of surgical site infections (SSIs) in this procedure is quite high, especially below the level of the knee. Antibiotic prophylaxis is not routinely prescribed, …

2021-12AlgemeenArtikel

The impact of anatomical changes during photon or proton based radiation treatment on tumor dose in glioblastoma dose escalation trials

Eline Hessen; Sebastian Makocki; Uulke A. van der Heide; Bas Jasperse; Lotte Lutkenhaus; Emmy Lamers (Lid Lectoraat); Eugene Damen; Esther G.C. Troost; Gerben R. Borst

Purpose/Objective: Most dose-escalation trials in glioblastoma patients integrate the escalated dose throughout the standard course by targeting a specific subvolume. We hypothesize that anatomical changes during irradiation may affect the dose coverage of this subvolume for both proton- and photon-based …

2021-09-28GezondheidArtikel

Characterization of automatic treatment planning approaches in radiotherapy

Geert Wortel; Dave Eekhout; Emmy Lamers (Lid Lectoraat); René van der Bel; Karen Kiers; Terry Wiersma; Tomas Janssen; Eugene Damen

Background and purpose: Automatic approaches are widely implemented to automate dose optimization in radiotherapy treatment planning. This study systematically investigates how to configure automatic planning in order to create the best possible plans. Materials and methods: Automatic plans were generated …

2021-07-13GezondheidArtikel

Exploring the relationship between light and subjective alertness using personal lighting conditions

Juliëtte van Duijnhoven (Onderzoeker); Mariëlle Aarts (Onderzoeker); Edwin van den Heuvel (Onderzoeker); Helianthe Kort (Lector)

Journal of Physics: Conference Series Paper • The following article is Open access Exploring the relationship between light and subjective alertness using personal lighting conditions J. van Duijnhoven1, M.P.J. Aarts1, E.R. van den Heuvel2 and H.S.M. Kort3,4 Published under licence by IOP Publishing …

2021GezondheidConferentiebijdrage

State of the art: the role of citrulline as biomarker in patients with chemotherapy- or graft-versus-host-disease-induced mucositis

I.M. Dekker; H Bruggink; Barbara van der Meij; N. Wierdsma

Purpose of review Serum or plasma citrulline levels are used as biomarker for a broad spectrum of intestinal functions. During high-dose chemotherapy, citrulline levels are decreased due to mucositis, a common side effect of chemotherapy. This may decrease intestinal function and result in diarrhea. …

2021AlgemeenArtikel

Analysis of radiation exposure data from common radiological procedures in Dutch hospitals

Bijwaard, H; de Vries, G; de Waard-Schalkx, I; van Welie, F; Haarmans-Jonkman, Sharon; Erenstein, H (Healthy Ageing, Allied Health Care And Nursing); Scheurleer, J; Roding, T; Middendorp, I V; van der Ploeg, T

INTRODUCTION: In the Netherlands, Diagnostic Reference Levels (DRLs) have not been based on a national survey as proposed by ICRP. Instead, local exposure data, expert judgment and the international scientific literature were used as sources. This study investigated whether the current DRLs are reasonable …

2020-08AlgemeenArtikel

Analysis of radiation exposure data from common radiological procedures in Dutch hospitals

Harmen Bijwaard (Lector); Geert de Vries (Lid Lectoraat); Ischa de Waard-Schalkx (Onderzoeker); Frank van Welie (Onderzoeker); S. Haarmans-Jonkman (Onderzoeker); H. Erenstein (Onderzoeker); Jelle Scheurleer (Docent); Thom Roding (Docent); I.V. Middendorp (Onderzoeker); T. van der Ploeg (Onderzoeker)

Introduction: In the Netherlands, Diagnostic Reference Levels (DRLs) have not been based on a national survey as proposed by ICRP. Instead, local exposure data, expert judgment and the international scientific literature were used as sources. This study investigated whether the current DRLs are reasonable …

2020GezondheidArtikel

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