HBO Kennisbank

Filter

12 Resultaten

Sorteer op:

Zocht je misschien: drugs, druk?

A Mycobacterial Antacid

Buter, Jeffrey

A Mycobacterial Antacid

2020GezondheidConferentiebijdrage

High diversity in SCCmec elements among multidrug-resistant Staphylococcus haemolyticus strains originating from paediatric patients; characterization of a new composite island

Farideh Hosseinkhani (Onderzoeker); Matthias Tammes Buirs (Student); Fereshteh Jabalameli (Onderzoeker); Mohammad Emaneini (Onderzoeker); Willem van Leeuwen (Lector)

Purpose. Staphylococcus haemolyticus has emerged as a highly antimicrobial-resistant healthcare-associated pathogen, in particular for patients admitted to neonatal intensive care. The objective of this study was to study the nature of SCCmec types among MDR-SH strains isolated from paediatric patients. Methodology. …

2018-07-01Natuur & LandbouwArtikel

High-quality genome sequence of the highly bacterium Staphylococcus haemolyticus, isolated from a neonatal bloodstream infection

Mohammad Emaneini (Onderzoeker); Farideh Hosseinkhani (Onderzoeker); Willem van Leeuwen (Lector)

Using Illumina HiSeq and PacBio technologies, we sequenced the genome of the multidrug-resistant bacterium Staphylococcus haemolyticus, originating from a bloodstream infection in a neonate. The sequence data can be used as an accurate reference sequence.

2017-07-20Natuur & LandbouwArtikel

Regional Expression Levels of Drug Transporters and Metabolizing Enzymes along the Pig and Human Intestinal Tract and Comparison with Caco-2 Cells

Stefan Vaessen (Lid Lectoraat); M.M.H. van Lipzig (Onderzoeker); Raymond Pieters (Lector); Cyrille Krul (Lector); Heleen Wortelboer (Onderzoeker); E. van de Steeg (Onderzoeker)

From TU Delft repository: "Intestinal transporter proteins and metabolizing enzymes play a crucial role in the oral absorption of a wide variety of drugs. The aim of the current study was to characterize better available intestinal in vitro models by comparing expression levels of these proteins and …

2017GezondheidArtikel

Monoterpene isolated from the essential oil of Trachyspermum ammi is cytotoxic to multidrug-resistant Pseudomonas aeruginosa and Staphylococcus aureus strains

Fereshteh Jabalameli (Onderzoeker); Farideh Hosseinkhani (Onderzoeker); Maryam Banar (Onderzoeker); Nafiseh Abdellahi (Onderzoeker); Morovat Taherikalani (Onderzoeker); Willem van Leeuwen (Lector); Mohammad Emaneini (Onderzoeker)

INTRODUCTION: The aim of this study was to determine whether an herbal extract containing monoterpene exhibited activity against multidrug-resistant Staphylococcus aureus and Pseudomonas aeruginosa isolated from clinical infection samples. METHODS: The essential oil of Trachyspermum ammi (L.) Sprague …

2016Natuur & LandbouwArtikel

Antibiotic use in children with acute respiratory or ear infections

Harald J. Hamre (Onderzoeker); Anja Glockmann (Onderzoeker); Reinhard Schwarz (Onderzoeker); David S. Riley (Onderzoeker); Erik Baars (Lector); Helmut Kiene (Onderzoeker); Gunver S. Kienle (Onderzoeker)

Children with acute respiratory or ear infections (RTI/OM) are often unnecessarily prescribed antibiotics. Antibiotic resistance is a major public health problem and antibiotic prescription for RTI/OM should be reduced. Anthroposophic treatment of RTI/OM includes anthroposophic medications, nonmedication …

2014-11-18GezondheidArtikel

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes

Fleuren, Wilco W M; Linssen, Margot M L; Toonen, Erik J M; van der Zon, Gerard C M; Guigas, Bruno; de Vlieg, Jacob; Dokter, Wim H A; Ouwens, D Margriet; Alkema, Wynand (Data Science For Life Science & Health)

Synthetic glucocorticoids are potent anti-inflammatory drugs but show dose-dependent metabolic side effects such as the development of insulin resistance and obesity. The precise mechanisms involved in these glucocorticoid-induced side effects, and especially the participation of adipose tissue in this …

2013-03-19AlgemeenArtikel

Hydroximic acid derivatives

Crul, Tim; Toth, Noemi; Piotto, Stefano; Literati-Nagy, Peter; Tory, Kalman; Haldimann, Pierre; Kalmar, Bernadett; Greensmith, Linda; Torok, Zsolt; Balogh, Gabor; Gombos, Imre; Campana, Federica; Concilio, Simona; Gallyas, Ferenc; Nagy, Gabor; Berente, Zoltan; Gungor, Burcin; Peter, Maria; Glatz, Attila; Hunya, Akos; Literati-Nagy, Zsuzsanna; Vigh, Laszlo; Hoogstra-Berends, Femke; Heeres, André (Biobased Ingredients And Materials); Kuipers, Irma; Loen, Lizette; Seerden, Jean-Paul; Zhang, Deli; Meijering, Roelien A M; Henning, Robert H; Brundel, Bianca J J M; Kampinga, Harm H; Koranyi, Laszlo; Szilvassy, Zoltan; Mandl, Jozsef; Sumegi, Balazs; Febbraio, Mark A; Horvath, Ibolya; Hooper, Philip L; Vigh, Laszlo

According to the "membrane sensor" hypothesis, the membrane's physical properties and microdomain organization play an initiating role in the heat shock response. Clinical conditions such as cancer, diabetes and neurodegenerative diseases are all coupled with specific changes in the physical state and …

2013AlgemeenArtikel

Org 214007-0

van Lierop, Marie-José C; Alkema, Wynand (Data Science For Life Science & Health); Laskewitz, Anke J; Dijkema, Rein; van der Maaden, Hans M; Smit, Martin J; Plate, Ralf; Conti, Paolo G M; Jans, Christan G J M; Timmers, C Marco; van Boeckel, Constant A A; Lusher, Scott J; McGuire, Ross; van Schaik, Rene C; de Vlieg, Jacob; Smeets, Ruben L; Hofstra, Claudia L; Boots, Annemieke M H; van Duin, Marcel; Ingelse, Benno A; Schoonen, Willem G E J; Grefhorst, Aldo; van Dijk, Theo H; Kuipers, Folkert; Dokter, Wim H A

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

2012-11-12AlgemeenArtikel

Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis

Duiker, E.; van der Heij-Meijer, Annemieke; van der Bilt, A. R. M.; Meersma, G.J.; Kooi, N.; van der Zee, A.G.J.; de Vries, E.G.E.; de Jong, Steven

Background: Drug resistance is a major problem in ovarian cancer. Triggering apoptosis using death ligands such as tumour necrosis factor-related apoptosis inducing ligand (TRAIL) might overcome chemoresistance. Methods: We investigated whether acquired cisplatin resistance affects sensitivity to recombinant …

2011-04-01AlgemeenArtikel

1 2

Over HBO Kennisbank