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The impact of anatomical changes during photon or proton based radiation treatment on tumor dose in glioblastoma dose escalation trials

Eline Hessen; Sebastian Makocki; Uulke A. van der Heide; Bas Jasperse; Lotte Lutkenhaus; Emmy Lamers (Lid Lectoraat); Eugene Damen; Esther G.C. Troost; Gerben R. Borst

Purpose/Objective: Most dose-escalation trials in glioblastoma patients integrate the escalated dose throughout the standard course by targeting a specific subvolume. We hypothesize that anatomical changes during irradiation may affect the dose coverage of this subvolume for both proton- and photon-based …

2021-09-28GezondheidArtikel

Predicting and implications of target volume changes of brain metastases during fractionated stereotactic radiosurgery

Eline Hessen (Onderzoeker); Jasper Nijkamp (Onderzoeker); Pim Damen (Onderzoeker); Michael Hauptmann (Onderzoeker); Bas Jasperse (Onderzoeker); Luc Dewit (Onderzoeker); Lotte Lutkenhaus (Onderzoeker); Emmy Lamers (Lid Lectoraat); Uulke van der Heide (Onderzoeker); Eugène Damen (Onderzoeker); Patrick Hanssens (Onderzoeker); Gerben Borst (Onderzoeker)

a b s t r a c t: Objective: To study the impact of target volume changes in brain metastases during fractionated stereotactic radiosurgery (fSRS) and identify patients that benefit from MRI guidance. Material and methods: For 15 patients (18 lesions) receiving fSRS only (fSRSonly) and 19 patients (20 …

2019GezondheidArtikel

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The impact of anatomical changes during photon or proton based radiation treatment on tumor dose in glioblastoma dose escalation trials

Predicting and implications of target volume changes of brain metastases during fractionated stereotactic radiosurgery

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