Objectives: Pulmonary hypertension is one of the leading causes of death in systemic sclerosis. Early detection and treatment of pulmonary hypertension in systemic sclerosis is crucial. Nailfold capillaroscopy microscopy, vascular autoantibodies AT1R and ETAR, and several candidate-biomarkers have the …

Onderzoek naar de profilering van antilichamen in de prognose en classificatie van systemische sclerose. Het doel van het onderzoek was om commercieel beschikbare diagnostische assays voor de detectie van SSc-geassocieerde autoantilichamen te vergelijken. Daarnaast werder onderzoek gedaan naar de coëxistentie …

Systemic sclerosis (SSc) is an autoimmune disease which is characterized by vasculopathy, tissue fibrosis and activation of the innate and adaptive immune system. Clinical features of the disease consists of skin thickening and internal organ involvement. Due to the heterogeneous nature of the disease …