Ubiquitin (Ub) is a protein which post-translationally modifies other proteins (its target substrates) and determines their cellular fate. Ub can label substrates for degradation, it can also alter the location of their substrates within a cell or even affect their activity. Chains can be formed via …

Studying images in social media poses specific methodological challenges, which in turn have directed scholarly attention toward the computational interpretation of visual data. When analyzing large numbers of images, both traditional content analysis as well as cultural analytics have proven valuable. …

BACKGROUND: Social inequalities in bodyweight start early in life and track into adulthood. Dietary patterns are an important determinant of weight development in children, towards both overweight and underweight. Therefore, we aimed to examine weight development between age 5 and 10 years by ethnicity, …

Purpose: There is growing international interest in the implementation of structured osteoarthritis management programs (OAMPs) to deliver best evidence osteoarthritis (OA) care. A consortium of researchers, clinicians and consumers concerned with optimising implementation of OAMPs have established the …

Technology has an ever increasing role in the day to day lives of individuals and societies. To provoke critical thought about the impact of new digital technology, the Technology Impact Cycle Tool (TICT) has been developed. In this paper, three psychological constructs: Performance Expectancy, Effort …

Many challenges that confront today’s society are complex and dynamic and require new perspectives to arrive at solutions that could not be found before. Finding such new perspectives is part of a process called reframing and one of its key stages is theme investigation. Understanding a problem thoroughly …

In the context of changing values, practices and working arrangements, the worlds of journalism and art converge. Evaluating these professions in conflux and beyond their (supposed) opposing ideologies and discourses, remains both controversial and complex. Through a critical hermeneutic analysis, this …

Open Innovation (OI) revolves around the idea that to survive, organisations must identify, plug into, and leverage external knowledge sources as a core process in innovation. The creation and guarding of a suitable level of organisational permeability in the daily practice of OI can be challenging for …

Compassionate conservation is based on the ethical position that actions taken to protect biodiversity should be guided by compassion for all sentient beings. Critics argue that there are 3 core reasons harming animals is acceptable in conservation programs: the primary purpose of conservation is biodiversity …

Recent developments in digital technology and consumer culture have created new opportunities for retail and brand event concepts which create value by offering more than solely marketing or transactions, but rather a place where passion is shared. This chapter will define the concept of ‘fashion space’ …