Welke verbetermogelijkheden zijn er voor de Sociaal-Economische Raad (SER) op het gebied van duurzame bedrijfsvoering, waarmee de SER op lange termijn een duurzaam strategisch beleid kan uitvoeren en daarmee een voorbeeldfunctie uitoefent?”

Numerous databases containing information about DNA, RNA, and protein variations are available. Gene‐specific variant databases (locus‐specific variation databases, LSDBs) are typically curated and maintained for single genes or groups of genes for a certain disease(s). These databases are widely considered …

The consistent and unambiguous description of sequence variants is essential to report and exchange information on the analysis of a genome. In particular, DNA diagnostics critically depends on accurate and standardized description and sharing of the variants detected. The sequence variant nomenclature …

There is now a convergence of two modes of genetic testing, that of testing a few candidate genes at a time based on suspicion of a specific genetic disease, and that of genomic testing, especially when a candidate gene(s) is not suspected or known. Both aim to interpret pathogenicity of identified genetic …

Objectives: A large portion of anogenital cancers is caused by high-risk human papillomavirus (hrHPV) infections, which are especially common in HIV-infected men. We aimed to compare the incidence and clearance of anal and penile hrHPV infection between HIV-infected and HIV-negative MSM. Design: Analyses …

DNA-based techniques are frequently used to confirm the relatedness of putative outbreak isolates. These techniques often lack the discriminatory power when analyzing closely related microbes such as E. coli. Here the value of Raman spectroscopy as a typing tool for E. coli in a clinical setting was …

The fungal species Trichoderma harzianum is widely used as a biological agent in crop protection. To verify the continued presence of this fungus on plant roots manually inoculated with T. harzianum strain T22, a Q-PCR was designed using specific probes for this particular strain. To develop these molecular …

Mobile Rapid-DNA devices have recently become available on the market. These devices can perform DNA analyses within 90 min with an easy ‘sample in–answer out’ system, with the option of performing comparisons with a DNA database or reference profile. However, these fast mobile systems cannot yet compete …