Wilms tumour suppressor gene (WT1) is essential for normal development of a kidney, it was also discovered as a major controller of mesenchymal-epithelial balance in general development of organs. In this project we use Wt1 and its role in the mesenchymal-epithelial balance to study the mechanism of …

Background Exercise therapy is the cornerstone of knee osteoarthritis (OA) management. In particular muscle strengthening exercise, targeting the characteristic loss of muscle strength present in knee OA, is a key factor for the beneficial effects reported for exercise therapy. The optimal training intensity …

Both climate change and human activity are the important drivers that can change hydrological cycle routs and affect the features of hydrological drought in river basins. The current study selects the Zayandeh Rud river Basin as a case study region in which to evaluate the influences of climate alteration …

Syngenta is one of the world’s leading agriculture companies. This report is made to create an overview on what activities have to be done for producing qualityseeds on sandy soils by taking the right decisions and using the right products. Firstly, this report describes the conditions required for cereal …

Objectives: The aim of this study was to assess the predictive value of PMA measurement for mortality. Background: Current surgical risk stratification have limited predictive value in the transcatheter aortic valve implantation (TAVI) population. In TAVI workup, a CT scan is routinely performed but …

Ik ben opgegroeid in een doodnormale rij woningen in een doodgewone straat. In het alledaagse van mijn herinneringen aan dat huis blijkt een verborgen romantiek te schuilen. Negen uitgeschreven herinneringen vormen de basis van dit plan. Uit de herinneringen is het ontwerp geboetseerd. Op de oevers …

Extreme winter weather conditions severely affect the transportation sector. Technologies such as Road Weather Information Systems provide live data on the road surface conditions to assist the road authorities in providing safe mobility. The main problem is, however, the limited number of such systems …

Maker education offers opportunities to stimulate the creativity of young people in various types of education. How to guide these learning processes, however, is an unexplored area for the supervisors (teachers and librarians). In the research-project presented, a professional learning community of …

In the Netherlands there is discussion about the best way to teach mathematics, especially in the case of primary school students. Being able to identify and understand pupils’ multiple problem solving strategies is one of the pillars of pedagogy. However, it is very demanding for teachers, since it …

In this paper, a general approach for modeling airport operations is presented. Airport operations have been extensively studied in the last decades ranging from airspace, airside and landside operations. Due to the nature of the system, simulation techniques have emerged as a powerful approach for dealing …