Formation of the pro-apoptotic death-inducing signaling complex (DISC) can be initiated in cancer cells via binding of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to its two pro-apoptotic receptors, TRAIL receptor 1 (TRAIL-R1) and TRAIL-R2. Primary components of the DISC are trimerized …

It is well-known that instead of changing course exactly at the edge, changing course when the sweep radius reaches the edge (i.e. changing course at distance R from the edge) generally yields higher probabilities of detection. In this article the authors shall investigate whether or not an even higher …

Nowadays the interest in Business Process Management (BPM) and Service Oriented Architecture (SOA) is rising enormously. There are a lot of software developers and consultancy firms that are jumping to the occasion and are selling Business Process Management Systems (BPMS) that are based on these concepts …

On the eve of the twenty-first century, it is a scandal that there are still people sleeping rough on our streets. This is not a situation we can continue to tolerate in a modern and civil society. These were the words of Tony Blair in his foreword to the policy document Rough Sleeping, The Government’s …