The demand of renewable energy in the European Union is increasing significantly in order to reduce CO2 emissions. Efforts are being made for further development of biomethane and hydrogen to use it as a clean and sustainable fuel for vehicles. However, biomethane and hydrogen contains impurities that …

Non-Small-Cell Lung Carcinoom (NSCLC) is een vorm van longkanker die wordt behandeld met Stereotactic Body Radiotherapy (SBRT) waarbij in minder fracties een hogere dosis wordt gegeven. Hierdoor is het belangrijk dat de PTV-marges optimaal klein zijn om de therapeutische ratio hoog te houden. Met Image-Guided …

Een uitdaging binnen radiotherapie van longtumoren is het feit dat deze gedurende de ademhaling bewegen. De mate van tumorbeweging heeft invloed op de grootte van het Planning Target Volume (PTV) en op de dosis in omliggende organs at risk (OARs). Een mogelijke oplossing voor het beperken van beweging …

Bestraling van longtumoren blijft een voortdurende uitdaging door beweging tijdens ademhaling (1). Een tumor kan, afhankelijk van de locatie, tot wel 20 millimeter bewegen in inferior-superior richting (2). Een afname van deze beweging kan resulteren in een lagere dosis in omliggende organen, ofwel Organs …

Background: Pseudomonas aeruginosa is a nosocomial pathogen that causes severe infections in immunocompromised patients. Biofilm plays a significant role in the resistance of this bacterium and complicates the treatment of its infections. In this study, the effect of lyticase and β-glucosidase enzymes …

Canalization, an intrinsic robustness of development to external (environmental) or internal (genetic) perturbations, was first proposed over half a century ago. However, whether the robustness to environmental stress (environmental canalization [EC]) and to genetic variation (genetic canalization) are …

From single-cell organisms to complex neural networks, all evolved to provide control solutions to generate context- and goal-specific actions. Neural circuits performing sensorimotor computation to drive navigation employ inhibitory control as a gating mechanism as they hierarchically transform (multi)sensory …

Dark homogenous fungal-based layers called biofinishes and vegetable oils are keyingredients of an innovative wood protecting system. The aim of this study was todetermine which of the vegetable oils that have been used to generate biofinishes onwood will provide carbon and energy for the biofinish-inhabiting …

What about people, hardware (biology) and software (culture)? Our construction starts with an egg cell and a sperm cell that is 83,000 times smaller (in this phase the female is certainly cooperative). The 2 cells double, and double, 47 times (247) resulting in the 140.737 billion (1.4 * 1014) complex …

Background: A nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) is a lymphoproliferative neoplasm with a fair prognosis, but the possibility of a malignant transformation into a diffuse large B-cell lymphoma (DLBCL) is high. DLBCL progresses aggressively. Introduction of rituximab into therapy …