Paratonie en andere motorische stoornissen bij dementie

Met de toenemende vergrijzing in ons land zal er ook een toename plaatsvinden van het aantal ouderen met dementie. Dementie, met als voornaamste oorzaak de ziekte van Alzheimer, wordt in het algemeen vooral gezien als een ziekte waarbij cognitieve problemen optreden. Dat er ook al in een vroeg stadium …

Rationale: Lean body mass, including muscle, is known to decrease with age, which may contribute to loss of physical function, an indicator of frailty. Moreover, low muscle thickness is considered an indicator of frailty in critically ill patients. However, little is known about the relationship between …

Objective: To predict mortality with the Tilburg Frailty Indicator (TFI) in a sample of community-dwelling older people, using a follow-up of 7 years. Setting and Participants: 479 Dutch community-dwelling people aged 75 years or older. Measurements: The TFI, a self-report questionnaire, was used to …

Background & aims: Malnutrition, frailty, physical frailty, and disability are common conditions in patients with chronic obstructive pulmonary disease (COPD). Insight in the coexistence and relations between these conditions may provide information on the nature of the relationship between malnutrition …

We tested the hypothesis that in human ageing a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance and altered mitochondrial function. Results showed that intramuscular total carnitine levels and acetylcarnitine levels were lower in (pre-)frail …

This study tested the hypothesis that in human aging, a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance, and altered mitochondrial function. We used a cross-sectional study design with well-matched fit and (pre-)frail old males and females, …

Frailty is the most common manifestation of serious health issues in the world, and it is becoming more prevalent worldwide as the aging population grows. Changes that occur in an individual during the aging process have physical, psychological, social, and environmental aspects that make an individual …

Met de toenemende vergrijzing in ons land zal er ook een toename plaatsvinden van het aantal ouderen met dementie. Dementie, met als voornaamste oorzaak de ziekte van Alzheimer, wordt in het algemeen vooral gezien als een ziekte waarbij cognitieve problemen optreden. Dat er ook al in een vroeg stadium …

Background: Frailty is considered highly prevalent in older age. Frailty causes a high risk of falls, disability, hospitalization, and mortality. This eventually might be the turning-point for older patients to shift from independent living to assisted living. Poor nutritional status might be an important …