Background Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine skin tumor with frequent local recurrence, lymph node involvement, distant metastasis, and a high mortality rate. Viscum album extracts (VAE) are a widely used adjunct in cancer treatment and show cytotoxic and immune-modulating …

Purpose : A structured, tailored exercise therapy strategy was found to significantly improve physical functioning, reduce pain and was safe for patients with knee osteoarthritis (OA) and severe comorbidity. The intervention was performed in a specialized, secondary care center. Before the intervention …

Late diagnosis of HIV remains a major challenge in the HIV epidemic. In Europe, about 50% of all people living with HIV are diagnosed late after infection has occurred. Insight into the reasons for late diagnoses is necessary to increase the number of early diagnoses and optimize treatment options. This …

Health problems may cause decreased productivity among working people. It is unclear if this also applies for people living with HIV (PLWH). This cross-sectional study compares data of PLWH of one of the main HIV treatment centres in the Netherlands (n = 298) to data of the general working population …

Background: Recent theoretical models emphasize the role of impulsive processes in alcohol addiction, which can be retrained with computerized Cognitive Bias Modification (CBM) training. In this study, the focus is on action tendencies that are activated relatively automatically. Objective: The aim of …

The following research seeks to enlarge the string quartet repertoire by making and performing original re-orchestrations of contemporary film music. It examines the art of storytelling and how to reproduce a cinematic drama on a smaller scale – divorced from its visual component. The basis of this project …

Dit onderzoek gaat over gebruikerservaringen, het gaat ook over roken en het gaat over stoppen met roken. Dat laatste is voor veel gebruikers blijkbaar moeilijk en daarom wordt op verschillende manieren ondersteuning geboden aan mensen die willen stoppen met roken. Een daarvan is Blended Smoking Cessation …

Arsenic contamination of groundwater is a major public health concern worldwide. The problem has been reported mainly in southern Asia and, especially, in Bangladesh. Slow-sand filters (SSF) augmented with iron were proven to be a simple, low-cost and decentralized technique for the treatment of arsenic-contaminated …

Cutaneous melanoma is a type of skin cancer that develops from benign melanocytes to one of the most aggressive types of skin tumors in human. In cutaneous melanoma progression, the metastasis phase is the most challenging phase to treat. To enable earlier treatment options, a better understanding of …

Background: More knowledge about characteristics of children and adolescents who need intensive levels of psychiatric treatment is important to improve treatment approaches. These characteristics were investigated in those who need youth Assertive Community Treatment (youth-ACT). Method: A cross-sectional …