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Towards a reporting guideline for developmental and reproductive toxicology testing in C. elegans and other nematodes

Monique van der Voet (Onderzoeker); Marc Teunis (Associate Lector); Johanna Louter-Van de Haar (Onderzoeker); Nienke Stigter (Onderzoeker); Diksha Balla (Onderzoeker); Martijn Rooseboom (Onderzoeker); Kimberley Wever (Onderzoeker); Cyrille Krul (Lector); Raymond Pieters (Lector); Marjolein Wildwater (Onderzoeker); Vera van Noort (Onderzoeker)

Implementation of reliable methodologies allowing Reduction, Refinement, and Replacement (3Rs) of animal testing is a process that takes several decades and is still not complete. Reliable methods are essential for regulatory hazard assessment of chemicals where differences in test protocol can influence …

2021GezondheidArtikel

Early Signs of Impaired Gut Function Affect Daily Functioning in Patients With Advanced Cancer Undergoing Chemotherapy

Barbara van der Meij; N.E.P. Deutz; RE Rodriguez; Marscha Engelen

Background Gastrointestinal symptoms are common during chemotherapy, but underlying disturbances in gut function and their impact on daily life are unclear. This study investigates gut function in a heterogenous group of cancer patients with gastrointestinal symptoms during chemotherapy and its relation …

2021AlgemeenArtikel

Construct validity of the OCTOPuS stratification algorithm for allocating patients with knee osteoarthritis into subgroups

Knoop, Jesper; Ostelo, Raymond W. J. G.; van der Esch, Martin (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen); de Zwart, Arjan; Bennell, Kim L.; van der Leeden, Marike; Dekker, Joost

BACKGROUND: We recently developed a model of stratified exercise therapy, consisting of (i) a stratification algorithm allocating patients with knee osteoarthritis (OA) into one of the three subgroups ('high muscle strength subgroup' representing a post-traumatic phenotype, 'low muscle strength subgroup' …

2021AlgemeenArtikel

Construct validity of the OCTOPuS stratification algorithm for allocating patients with knee osteoarthritis into subgroups.

J. Knoop; R.W.J.G. Ostelo; M. van der Esch; A. de Zwart; K.L. Bennell; M van der Leeden; J Dekker

2021AlgemeenArtikel

Awake proning in patients with COVID-19

Stilma, W. (Centre Of Expertise Urban Vitality); Bos, L.; Pisani, L.; Schultz, M.; Paulus, F.

Introduction: Awake proning may result in lower intubation and mortality rates in COVID-19 patients with hypoxemia refractory to simple oxygen therapy. Aims. To summarize available evidence for benefit and develop a set of pragmatic recommendations for awake proning in COVID-19 patients. Methods. An …

2021AlgemeenConferentiebijdrage

Blended home-based exercise and dietary protein in community-dwelling older adults: a cluster randomized controlled trial

van den Helder, Jantine (Centre Of Expertise Urban Vitality); Mehra, Sumit; van Dronkelaar, Carliene (Centre Of Expertise Urban Vitality); ter Riet, Gerben; Tieland, Michael (Centre Of Expertise Urban Vitality); Visser, Bart (Centre Of Expertise Urban Vitality); Kröse, Ben J.A.; Engelbert, Raoul H.H. (Centre Of Expertise Urban Vitality); Weijs, Peter J.M. (Centre Of Expertise Urban Vitality)

Background: Effective and sustainable interventions are needed to counteract the decline in physical function and sarcopenia in the growing aging population. The aim of this study was to determine the 6 and 12 month effectiveness of blended (e-health + coaching) home-based exercise and a dietary protein …

2020-12AlgemeenArtikel

Knowledge and attitude of nursing students regarding older adults' sexuality

Wilschut, V.F.C. (Vivian) (Researcher); Pianosi, B. (Birgit) (Professor); Van os-Medendorp, H. (Harmieke) (Researcher); Elzevier, H.W. (Henk) (Professor); Jukema, J.S. (Jan) (Lector); van Ouden, M.E.M.. (Marjolein) (Lector)

CC-BY Gepubliceerd in Nurse Education Today, January 2021https://www.sciencedirect.com/science/article/pii/S0260691720314933Background: Although older adults are sexual, sexuality is infrequently discussed with them by health care professionals. Nursing students, as future professionals, can make …

2020-11-01AlgemeenArtikel

Knowledge and attitude of nursing students regarding older adults’ sexuality

Ouden, M. (Marjolein) den (Lector); Wilschut, V.F.C.. (Vivian); Os-Medendorp, H. (Harmieke); Jukema, J.S. (Jan)

CC-BY Nurse Education Today, 2021, January Background: Although older adults are sexual, sexuality is infrequently discussed with them by health care professionals. Nursing students, as future professionals, can make an important contribution by developing competences in discussing intimacy and sexuality …

2020-11-01AlgemeenArtikel

Big data-analyse voor detectie overbelasting topsporters.

Nijland, Rick (Praktijkgerichte Sportwetenschap); Brauers, Jur; Otter-Drost, Ruby Tina Ardi (Praktijkgerichte Sportwetenschap); Brink, Michel; de Jong, Johan (Healthy Lifestyle, Sports And Physical Activity)

De balans tussen de belastbaarheid van sporters en de belasting moeten zo goed mogelijk afgestemd zijn om optimale trainingseffecten te realizeren. Er wordt onderscheid gemaakt tussen externe en interne trainingsbelasting, wat duidt op de belasting die extern of intern door de sporter wordt ervaren. …

2020-10-27AlgemeenRapport

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients

DecubICUs Study Team

PURPOSE: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU …

2020-10AlgemeenArtikel

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