Upcycling has been embraced by circular economy enthusiasts, policy-makers and collaborative initiatives across Europe. Early studies describe upcycling as a concept aimed at resource conservation by keeping products, components and materials at their highest potential value across consecutive product …

Patients on general wards are at risk of complications, often associated with deviations in vital signs. Unfortunately, the currently used manual method of intermittently measuring vital signs is not optimal, potentially leading to late recognition and treatment of complications, and sometimes with serious …

Objective: To prepare a set of statements for randomised clinical trials (RCT) integrity through an international multi-stakeholder consensus. Methods: The consensus was developed via: multi-country multidisciplinary stakeholder group composition and engagement; evidence synthesis of 55 systematic reviews …

Owing to the non-toxic, nonimmunogenic effects and high affinity to specific molecules, some single-stranded oligonucleotides, namely aptamers, can be exploited in biochemical applications to deliver bioactive elements and interact with the desired targets. Among many identified aptamers, D#7 was utilized …

Introduction Although the prevalence of dementia increases among people with severe/profound intellectual (and multiple) disabilities (SPI(M)D), dementia in people with SPI(M)D is not yet fully understood. Therefore, this study aimed to characterize the natural history of dementia in people with SPI(M)D, …

Young widowhood, conceptualized as the loss of one’s spouse before the age of 50, is a profoundly painful and distressing loss (Den Elzen, 2017, 2018). The literature on young widowhood shows the death of a partner generally causes a fragmentation of the self, as it violates expectations of the normal …

Sepsis is a life-threatening organ dysfunction caused by a dysregulated immune response to infection. It is the number one cause of death in the Intensive Care Unit (ICU), accounting for 6 million casualties every year. Unfortunately, all clinical trials in the last decade failed due to the highly complex …

Despite continuous efforts in various economies, amongst others in South-East Asia, the full potential of social entrepreneurship (SE) is difficult to realize (STEPup project comparative study findings). Challenges that need to be addressed include the lack of skilled employees, business understanding …

Dairy and other animal products play an important role in the diet of the majority of the population. However, there are a lot of sustainability concerns regarding dairy production due to high environmental impacts. Therefore, there is a need to develop a more sustainable dairy substitute. One of the …

In maart van 2022 zijn grote delen van Suriname overstroomd wegens hevige regenval in de eerste maanden van dat jaar. Naar schatting zijn 12,000 bewoners uit 35 dorpen, verspreid door hele land, maandenlang het slachtoffer geweest van deze extreme wateroverlast. Uit verschillende interviews met bewoners …