This literature review will focus on how CRISPR/Cas can be used in curing diabetes. CRISPR is a newly discovered genetical engineering tool that was first found in bacteria and it has an important immune function, protecting them from viral infections by cutting the viral DNA, thereby disabling it. Researchers …

The purpose of this research is to validate and optimize the synthesis of the natively linked α-UbADPr & β-UbADPr (19α,β) on arginine 42 to further study in the enzymes of Legionella Pneumophilia. In the synthesis of UbADPr the sub goal was to synthesize as much as possible of two molecules (building …

Er is een HPLC-UV/VIS/DAD-methode geoptimaliseerd en gevalideerd voor de gehalte- bepaling van Bisoprolol Fumaraat (BF). De maatschappelijke relevantie hiervan is dat Innogenerics door een gevalideerde methode Europese bevoegdheid krijgt/heeft om farmaceutische middelen van buiten de EU vrij te geven …

The use of H-ZSM-5 with various binders (Al2O3, SiO2, and kaolinite, 10 wt% on catalyst formulation) for the catalytic conversion of glycerol to bio-based aromatics (GTA) was investigated in a continuous bench-scale unit at a pyrolysis temperature of 450 °C, catalytic upgrading temperature of 500 °C, …

Kombucha is a drink made from fermented sweetened tea. Kombucha has a sweet and sour taste, it is slightly sparkling and in recent years, the drink has become increasingly popular in the western world. This surge in popularity is in part due to the supposed health benefits. The exact chemical composition …

Artikel in Agro & Chemie over de productie van exogene ketonen in het projecten Circulaire Biopolymeren Waardeketens voor PHA en Cellulose.

In dit project is er een LC-MS/MS-methode ontwikkeld voor de vijf schildklierhormonen T4, T3, rT3, TA3 en TA4. De volgende prestatiekenmerken zijn bepaald met behulp van de LC-MS/MS: Lineariteit, onderste kwantificatielimiet (LLOQ), precisie, carry- over en matrix effect. Er wordt geconcludeerd dat …

SMPD4 is a neutral sphingomyelinase that plays an important role in sphingolipid metabolism. Sphingolipids are a family of lipid molecules abundantly present in the brain where they play an important role in the brain development and function due to their essential cellular role as structural components …

The coronavirus disease-19 (COVID-19) pandemic still poses serious threats to global public health. Therefore, the scientific community is desperately looking for suitable vaccines and pharmacological treatment options. This thesis completes the internship at Specs Compound Handling BV and describes …

In 2027 dienen normoverschrijdingen van gewasbeschermingsmiddelen in waterlichamen 0% te zijn om goede status ecologie en chemie te behalen. Om dit te behalen is het van belang dat maatregelen ter preventie van gewasbeschermingsmiddelen worden uitgevoerd in Friesland. Om hieraan bij te dragen, is dit …