The COVID–19 pandemic led to local oxygen shortages worldwide. To gain a better understanding of oxygen consumption with different respiratory supportive therapies, we conducted an international multicenter observational study to determine the precise amount of oxygen consumption with high-flow nasal …

Nutritional intervention studies in older adults with malnutrition aim to improve nutritional status. Although these studies show a significant gain in body weight, there is inconsistent evidence of clinical effectiveness on muscle strength and mortality. This study aimed to examine the effects of nutritional …

Objective To evaluate the effectiveness of psychosomatic therapy versus care as usual in primary care for patients with persistent somatic symptoms (PSS). Methods We conducted a pragmatic, two-armed, randomised controlled trial among primary care patients with PSS in the Netherlands that included 39 …

Background Hospital admissions are common in the last phase of life. However, palliative care and advance care planning (ACP) are provided late or not at all during hospital admission. Aim To provide insight into the perceptions of in-hospital healthcare professionals concerning current and ideal practice …

Als in het voorjaar de watertemperatuur stijgt, maken oesters zich klaar voor de voortplanting. Dit is het startpunt van nieuwe oesters. Zodra de bevruchting van eicellen plaats heeft gevonden, worden er oesterlarven gevormd. Maar wanneer zijn deze oesterlarven waarneembaar in de waterkolom en komen …

Introduction Radical cystectomy (RC) is the standard treatment for patients with non-metastatic muscle-invasive bladder cancer, as well as for patients with therapy refractory high-risk non-muscle invasive bladder cancer. However, 50–65% of patients undergoing RC experience perioperative complications. …

Background A high sedentary time is associated with increased mortality risk. Previous studies indicate that replacement of sedentary time with light- and moderate-to-vigorous physical activity attenuates the risk for adverse outcomes and improves cardiovascular risk factors. Patients with cardiovascular …

De eerste ventilatoire drempel (VT1) is de intensiteit waarbij het niveau van CO2uitstoot voor het eerst boven het niveau van O2 inname uitstijgt. Men wordt beperkt door de accumulatie van de CO2, waardoor niet langer oneindig door kan worden gegaan met de activiteit die op dat moment wordt uitgevoerd. …

The aim of this study was to develop and validate an algorithm that can identify the type, frequency, and duration of activities common to intensive care (IC) patients. Ten healthy participants wore two accelerometers on their chest and leg while performing 14 activities clustered into four protocols …

In this article, it is argued that In polarization, we fixate on two poles, like true and false, news versus fake news, real versusfalse, or in a social context, rich versus poor, and good versus bad. This is an instance of singular thinking, because a third factor is overlooked, being the area between …