BACKGROUND: Glucocorticoids (GCs) control expression of a large number of genes via binding to the GC receptor (GR). Transcription may be regulated either by binding of the GR dimer to DNA regulatory elements or by protein-protein interactions of GR monomers with other transcription factors. Although …

Purpose In the Netherlands 43% of nursing home residents have visual impairments1. Visual impairments can be a result of the normal ageing process or specific diseases. Vision impairment can result in the loss of basic visual abilities: acuity, contrast sensitivity, or visual field 2. In 56% of the cases …

Thermal comfort -the state of mind, which expresses satisfaction with the thermal environment- is an important aspect of the building design process as modern man spends most of the day indoors. This paper reviews the developments in indoor thermal comfort research and practice since the second half …

A research into classroom interaction (behaviour and communication) between teachers and pupils in the light of social justice. The research is based on the concern that educational praxis, defined as 'practice which implies a conscious awareness of the practitioners that their actions are morally committed, …

Creative SMEs are heavily focusing on the creating process designing new products and services. Consequently, their managers tend to loose contact with crucial management issues. Especially their knowledge of the financial aspects of their business can be so limited that they fail to connect with the …

The past century has been a century characterized by human suffering and conflict. The establishment of the United Nations in the aftermath of World War II has brought the pressing issue of human rights to the attention of the international world. However, the UN’s reluctance to act on occasions of …

Students' educational careers in Higher Education: a search into key factors regarding study outcome One of the political goals of the EU is to develop 'the most competitive knowledge-based economy in the world by 2010'. The Dutch knowledge economy faces an increased demand for highly-educated inhabitants, …

There has probably never been such an intense debate about the layout of the countryside as the one that is currently raging. There are serious concerns about the landscape, which is being rapidly transformed by urbanization and everything associated with this process, and not only in the Netherlands …

This book, ‘Outreach work and imminent eviction: RAAK research’, is a report of the results obtained from the examination of these innovations. The first chapter contains a description of the pilot projects, which brought together care workers from the Blankenberg Foundation and Dynamo for early intervention …