QUESTIONS: What are the perceived reasons for people with chronic obstructive pulmonary disease (COPD) to be physically active or sedentary? Are those reasons related to the actual measured level of physical activity? DESIGN: A mixed-methods study combining qualitative and quantitative approaches. PARTICIPANTS: …

BACKGROUND: Understanding of the consequences of a neuromuscular disease (NMD) can improve when a valid sample of disease-specific categories based on the International Classification of Functioning, Disabilities, and Health (ICF) is available. OBJECTIVE: To examine the content validity of the initial …

Musculoskeletal pain is caused by risk factors for acquiring pain and prognostic factors for the persistence of prolonged pain and is the number one causal reason for restricted participation at work. Many studies have been performed on the reasons for acquiring and the continuance of musculoskeletal …

INTRODUCTION: To provide a state of the art on diagnostics, clinical characteristics, and treatment of paediatric generalised joint hypermobility (GJH) and joint hypermobility syndrome (JHS). METHOD: A narrative review was performed regarding diagnostics and clinical characteristics. Effectiveness of …

Background: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients. Methods: Baseline data from the …

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

OBJECTIVE: To examine the intelligibility and psychometric properties of the modified Dutch language version of the Work Limitations Questionnaire (WLQ) (WLQ-mdlv).

QUESTION: Do negative expectations in patients after the onset of acute low back pain increase the odds of absence from usual work due to progression to chronic low back pain? DESIGN: Systematic review with meta-analysis of prospective inception cohort studies. PARTICIPANTS: Adults with acute or subacute …

Thirty years ago, in the summer of 1982, I was introduced to pediatric nursing during my internship in the Sophia Children’s Hospital, Academic Hospital Rotterdam (now Erasmus MC). One of my unforgettable patients was Dirk, a 24-year-old man with cystic fibrosis (CF), who spent his time in hospital in …

This article presents the life stories of four older women in Vienna in order to better understand the role of occupation in the course of ageing. A qualitative life-story method in the narrative tradition was used as a design of this multiple case study. The stories presented extend beyond an illness …