Introduction. Despite the high number of inactive patients with COPD, not all inactive patients are referred to physical therapy, unlike recommendations of general practitioner (GP) guidelines. It is likely that GPs take other factors into account, determining a subpopulation that is treated by a physical …

Dementia and movement disorders. With a greying European society the consequences are already visible with an increase of the prevalence of Alzheimer’s disease and other age-related neurodegenerative and mental disorders. Therefore it is no surprise that the health care cost of brain disease is expected …

Movement disorders and inactivity in dementia. Movement disorders in dementia An interesting article by Ramakers et al in 2007 showed that 5 years prior to the diagnosis of dementia these people significantly more often visited their home physician in contrast with cognitive healthy age matched controls. …

Cardiovascular disease is an important cause of disability in activities of daily living (ADL) through its effect on physical functioning. However, it is unclear whether subclinical vascular abnormalities and rate of change in subclinical vascular abnormalities is also associated with an impaired physical …

Doel: Onderzoeken welke therapie, fotodynamische therapie met verteporfine (PDT), anti-vascular endothelial growth factor (anti-VEGF) of combinatietherapie (PDT met anti-VEGF), het meest positieve effect op de visus en de minste complicaties heeft bij patiënten met choroidale neovascularisatie (CNV). Methode: …

Full text via link. This study compares the reliability and reproducibility of flow-mediated dilatation (FMD) and peripheral arterial tonometry (PAT) to assess endothelial function. Eighteen volunteers with coronary heart disease underwent simultaneous testing of FMD by means of brachial artery ultrasound …

BACKGROUND: Paratonia is a progressive motor problem that is observed in individuals with dementia and is not a well-known phenomenon. This study explores the development and risk factors of paratonia in moderate stage dementia patients. METHODS: A multi-center, longitudinal, one-year follow-up cohort …

The invention relates to a novel class of [1,4]-benzodiazepine derivatives, processes for their preparation, intermediates usable in these processes, and pharmaceutical compositions containing the compounds. Other aspects of the invention are directed to the use of said [1,4]-benzodiazepine derivatives …

Living independently is an important component of quality of life. Cardiovascular diseases are prominent among the chronic conditions that predispose elderly people to functional limitations and disability, which impair quality of life. Insight into factors that play a role in the development process …

BACKGROUND: Paratonia is one of the associated movement disorders characteristic of dementia. The aim of this study was to develop an assessment tool (the Paratonia Assessment Instrument, PAI), based on the new consensus definition of paratonia. An additional aim was to investigate the reliability and …