Aims Genetic hypertrophic cardiomyopathy (HCM) is caused by mutations in sarcomere protein-encoding genes (i.e. genotype-positive HCM). In an increasing number of patients, HCM occurs in the absence of a mutation (i.e. genotype-negative HCM). Mitochondrial dysfunction is thought to be a key driver of …

During an interview at Georgetown University’s School of Foreign Service one student questioned Prime Minister Rutte about an official apology for slavery. The Dutch Prime Minister assured that each island-nation to whom the Kingdom apologized “has full power to decide to leave the Kingdom. They are …

Treatment guidelines difer signifcantly, not only between Europe and North America but also among European coun tries [1–4]. Reasons for these diferences include antimi crobial resistance patterns, accessibility to and reimburse ment policies for medicines, and culturally and historically determined …

Roughly half of all men in prison are fathers of minor children. Despite the high prevalence of fatherhood in prisons, little is known about imprisoned fathers’ needs regarding fatherhood and family relationships. In prisons for men, limited attention is given to men’s roles as fathers and the difficulties …

Background In adolescents with non-pathological and pathological joint hypermobility, gait deviations have been associated with pain and fatigue. It remains unclear what distinguishes the non-pathological form of joint hypermobility (JH) from pathological forms (i.e. hypermobile Ehlers-Danlos syndrome …

We present an evaluation of tools for assessing the impact of AI in the Dutch media sector. Our evaluation of the ECP AIIA tool shows the need for clear guidelines in the adoption of various AI applications within Dutch media organisations. We conclude that the adoption of impact assessment tools, such …

Values, representing higher abstract goals in life, receive increasing attention in branding literature and practice. However, understanding of how values drive consumer behavior is limited. This research contributes to a better understanding of the importance of values and value types in marketing communications …

Few people I know act likea magnet in the way Laura does. If you hear her speak, see her move, enjoy her smile - you can't help but want to be a part of what makes her heart beat faster. She radiates passion for her dream topic biomimicry and before you know it you're caught in that dream. From the day …

How to think from human entanglement in nonhuman life rather than from an assumption of separation and exception? How to put a non-universalizing, dehumanist ethics of knowledge into practice? How to practice a politics of knowledge in relation to nonhuman animals, built on the principle of differential …

Built on and inspired by existing knowledge, we have conceptualised a model in which two different user types (occupants and facility managers) are positioned to the building and its climate and regulatory systems. Thus, a feedback loop and interaction take place among all actors involved. The users, …