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Assessment of biopsychosocial complexity and health care needs

van Reedt Dortland, Arianne K.B.; Peters, Lilian L.; Boenink, Annette D.; Smit, Jan H.; Slaets, Joris P.J.; Hoogendoorn, Adriaan W.; Joos, Andreas; Latour, Corine H.M. (Faculteit Gezondheid); Stiefel, Friedrich; Burrus, Cyrille; Guitteny-Collas, Marie; Ferrari, Silvia

OBJECTIVES: The INTERMED Self-Assessment questionnaire (IMSA) was developed as an alternative to the observer-rated INTERMED (IM) to assess biopsychosocial complexity and health care needs. We studied feasibility, reliability and validity of the IMSA within a large and heterogeneous international sample …

2017-05-01AlgemeenArtikel

The natural history of children with joint hypermobility syndrome and Ehlers–Danlos hypermobility type: a longitudinal cohort study

M.C. Scheper; L.L. Nicholson; R.D. Adams; L. Tofts; V. Pacey

Objectives The objective of the manuscript was to describe the natural history of complaints and disability in children diagnosed with joint hypermobility syndrome (JHS)/Ehlers–Danlos-hypermobility type (EDS-HT) and to identify the constructs that underlie functional decline. Methods One hundred and …

2017-04-18GezondheidArtikel

Validity of the modified Berg Balance Scale in adults with intellectual and visual disabilities

Dijkhuizen, Annemarie; Krijnen, Wim P (Statistical Techniques For Applied Research); van der Schans, Cees (Healthy Ageing, Allied Health Care And Nursing); Waninge, Aly (Participation And Health Of Persons With Intellectual And Visual Disabilities)

Background A modified version of the Berg Balance Scale (mBBS) was developed for individuals with intellectual and visual disabilities (IVD). However, the concurrent and predictive validity has not yet been determined. Aim The purpose of the current study was to evaluate the concurrent and predictive …

2017-03-01AlgemeenArtikel

Predictive models reduce talent development costs in female gymnastics

Johan Pion; A. Hohmann; Liu Tianbiao; M. Lenoir; Veerle Segers

2017AlgemeenArtikel

Intra- and inter-laboratory validation of an innovative huFcεRIα-RBL-2H3 degranulation assay for in vitro allergenicity assessment of whey hydrolysates

Marjan Gros; Linda Cox; Johan Garssen; Niels de Jong; Diana Kegler; Reiko Teshima; Peter J. Simons; Laura Kruijssen; Manon van Roest; Raymond Pieters (Lector); Léon M.J. Knippels; Marieke Smits (Lid Lectoraat); Marc Teunis (Lid Lectoraat); Karen Knipping; Louis Boon

from the article: "Cow's milk-derived whey hydrolysates are milk substitutes for cow's milk allergic infants. Safety assessment of these hydrolysates is crucial. Currently, huFcεRIα-RBL-2H3 cells, sensitized with serum IgE from cow's milk allergic patients, are used to assess in vitro residual allergenicity. …

2016-02-24Natuur & LandbouwArtikel

Characteristics of daily life gait in fall and non fall-prone stroke survivors and controls

Mirjam Pijnappels; Sjoerd M. Bruijn; Kimberley M. Schooten; Jaap H. van Dieën; Harriët Wittink (Lector); Michiel Punt (Lid Lectoraat)

Background: Falls in stroke survivors can lead to serious injuries and medical costs. Fall risk in older adults can be predicted based on gait characteristics measured in daily life. Given the different gait patterns that stroke survivors exhibit it is unclear whether a similar fall-prediction model …

2016GezondheidArtikel

Validation of predictive models for smart control of thermal and electrical energy storage

Leeuwen, R.P. (Richard) van (Researcher); Wit, J.B. (Jan) de (Lector); Lei, Z. (Zhu) (Student)

A transition of today’s energy system towards renewableresources, requires solutions to match renewable energy generationwith demand over time. These solutions include smartgrids, demand-side management and energy storage. Energycan be stored during moments of overproduction of renewableenergy and used …

2015-07-01AlgemeenConferentiebijdrage

Longitudinal study of repeated sprint performance in youth soccer players of contrasting maturity status

V. Duarte; J. Valente dos Santos; V. Severino; Marije Elferink-Gemser; R. Philippaerts; M. Coelho e Silva; A. Seabra; A. Figueiredo; S. Cumming; R. Martins

The purpose of the study was to evaluate the developmental changes in performance in a repeated-sprint ability (RSA) test in young soccer players of contrasting maturity status. A total of 83 regional level Portuguese youth soccer players, aged 11- 13 years at baseline was assessed annually. Stature, …

2012AlgemeenArtikel

The impact of delirium in the prediction of In-Hospital Mortality in Intensive Care patients

Martijn Peters; Lisette Schoonhoven; Peter Pickkers; Pieter Leffers; Mark van den Boogaard; Hans van der Hoeven; Pieter Dagnelie

Predictive models, such as acute physiology and chronic health evaluation II (APACHE-II), are widely used in intensive care units (ICUs) to estimate mortality. Although the presence of delirium is associated with a higher mortality in ICU patients, delirium is not part of the APACHE-II model. The aim …

2010AlgemeenArtikel

Target validation in silico

Alkema, Wynand (Data Science For Life Science & Health); Rullmann, Ton; van Elsas, Andrea

Genomics has multiplied the number of targets for new therapeutic interventions, but this has not yet lead to a marked increase of pharma pipeline outputs. The complexity of protein function in higher order biological systems is often underestimated. Translation from in vitro and in vivo results to the …

2006-09-16AlgemeenArtikel

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