We tested the hypothesis that in human ageing a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance and altered mitochondrial function. Results showed that intramuscular total carnitine levels and acetylcarnitine levels were lower in (pre-)frail …

PURPOSE: Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but little is known on their relative effect on the 30-day survival after ICU admission. The primary aim of this study was to describe the prevalence …

Background: Frailty is considered highly prevalent in older age. Frailty causes a high risk of falls, disability, hospitalization, and mortality. This eventually might be the turning-point for older patients to shift from independent living to assisted living. Poor nutritional status might be an important …

Background Interprofessional education is promoted as a means of enhancing future collaborative practice in healthcare. We developed a learning activity in which undergraduate medical, nursing and allied healthcare students practice interprofessional collaboration during a student-led interprofessional …

Frailty and Physical Therapy講演要旨 （Abstract）The speed of ageing differs from country to country, but ageing is worldwide happening more quickly than in the past. We live in a dangerous world and all kinds of negative influences like stress or poor nutrition causes random molecular damage with an accumulation …

Abstract People over 65 years of age constitute over 80% of patients with heart failure (HF) and the incidence of HF is 10 per 1,000 in people aged above 65 years. Approximately 25% of older patients with HF exhibit evidence of frailty. Frail patients with cardiovascular disease (CVD) have a worse prognosis …

Frailty is a disputed but important concept in the care of older people. The agreed definition ( Fried et al 2001) is clinically driven and focusses on physical components and incapacity. But frailty is determined not only by disability and comorbidity. How do those defined by others as frail – perceive …

Introduction Many health care interventions have been developed that aim to improve or maintain the quality of life for frail elderly. A clear overview of these health care interventions for frail elderly and their effects on quality of life is missing. Purpose To provide a systematic overview of the …

Ageing brings about physiological changes that affect people’s thermal sensitivity and thermoregulation. The majority of older Australians prefer to age in place and modifications to the home environment are often required to accommodate the occupants as they age and possibly become frail. However, modifications …

Background: This study investigated the trajectories of decline in individual instrumental activities of daily living (IADL) with aging and the effect of hearing loss, vision loss, or dual sensory loss on these trajectories in community-living frail older persons. Method: This longitudinal population-based …