Tumor necrosis factor alpha (TNF-α) and its key role in modulating immune responses has been widely recognized as a therapeutic target for inflammatory and neurodegenerative diseases. Even though inhibition of TNF-α is beneficial for the treatment of certain inflammatory diseases, total neutralization …

This research study aims to determine the most suitable soil stabilization method for ensuring a stable and sustainable foundation for the design of a railway embankment expansion between Zoeterwoude East and Hazerswoude-Rijndijk. The research question is addressed through a comprehensive analysis using …

The following paper refers to the final thesis for the curriculum at HZ University of Applied Science and was carried out at the request of the Italian firm Aig Associati and Partner. The structural team of the architecture and engineering firm requested a study on the most effective and least time-consuming …

The findings suggest that CVT may be used as therapy in ABI populations with promising results. Both patient self-assessment and objective voice measures demonstrate improved voice function. Given the longitudinal nature of recovery in ABI patients, more studies are needed to qualify at which stage(s) …

Many ARM Cortex-M-based microcontrollers include tracing features which allow monitoring hardware events (e.g. exceptions occurring, a specific instruction being executed or a specific address range being accessed by the CPU). Tracing enables non-intrusive insight into software execution (i.e. software …

The recent advancements in machine learning (ML) techniques have significantly improved the performance in various natural language processing (NLP) tasks, particularly in deep learning with the transformer architecture. Despite their promising applications in different domains, these innovations have …

In their developmental model, Stodden et al. (2008) propose age- dependent relations between motor competence, physical activity, perceived motor competence, physical fitness, and weight status that can lead to a spiral of (dis)engagement. The goal of this study was to explore these relations in a large …

Background Hospital admissions are common in the last phase of life. However, palliative care and advance care planning (ACP) are provided late or not at all during hospital admission. Aim To provide insight into the perceptions of in-hospital healthcare professionals concerning current and ideal practice …

The number of Electric Vehicles (EVs) is expected to increase exponentially in the coming years. The growing presence of charging points generates a multitude of interactions between EV users, particularly in metropolitan areas where a charging infrastructure is largely part of the public domain. There …

A resource optimization methodology is proposed for application in long range wide area networks (LoRaWANs). Using variable neighborhood search (VNS) and a minimum-cost spanning tree algorithm, it reduces the implementation and the maintenance costs of such low power networks. Performance evaluations …