Lasiocarpine and riddelliine are pyrrolizidine alkaloids (PAs) known to cause liver toxicity. The aim of this study was to predict the inter-species and inter-ethnic human differences in acute liver toxicity of lasiocarpine and riddelliine using physiologically based kinetic (PBK) modelling based reverse …

The demand of renewable energy in the European Union is increasing significantly in order to reduce CO2 emissions. Efforts are being made for further development of biomethane and hydrogen to use it as a clean and sustainable fuel for vehicles. However, biomethane and hydrogen contains impurities that …

Fraeylemaborg is a noble house in an earthquake-stricken area of the Netherlands due to the induced seismicity events in the region. The structure is located in the middle of the town of Slochteren which gave its name to the largest gas field in the world upon its discovery in 1959. The gas extraction …

Full text via link. In September 2015, a four year project on the working alliance with mandated clients started. The project was facilitated by a RAAK-PRO grant of the Dutch Organisation of Scientific Research (NWO) and carried out by researchers of the University of Applied Sciences Utrecht. The project …

Limited evidence is available about (non)-representativeness of participants in health-promoting interventions. The Dutch Healthy Primary School of the Future (HPSF)-study is a school-based study aiming to improve health through altering physical activity and dietary behaviour, that started in 2015 (registered …

This study gains insight into impact of professional identity tensions in terms of affective appraisal and behavioral response. Data consisted of 126 semi-structured reflective journals from early career teachers collected during one school year. Affective appraisals were 'low' (no impact on daily functioning, …

The case study assesses the question ‘how can Scope best utilise the critical success factors of Scope One to gain market share?’, by focusing on identifying and analysing the critical success factors of Scope One. A framework was devised from four project management theories and two agile software development …

Inleiding: Huidkanker is de meest voorkomende vorm van kanker in Nederland. Niet-melanocytaire huidkanker (basaalcelcarcinoom en plaveiselcelcarcinoom) betreft samen ongeveer 90% van alle voorkomende soorten huidkanker. De meerderheid hiervan kan het beste chirurgisch verwijderd worden, waarbij de functionaliteit …