RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-function (LoF) variants in GRIN2B, resulting in dysfunction of the GluN2B subunit-containing N-methyl-d-aspartate receptor (NMDAR). Recently, in vitro experiments showed that …

Purpose. We aimed to evaluate the potential for implementing exercise interventions for patients with breast cancer in the Netherlands, based on findings of the Dutch randomized controlled trials in this population. Methods. We evaluated the implementation of four Dutch exercise trials retrospectively, …

Despite continuous improvement, lifelong learning, and plan-do-check-act cycles, every new day the planet is a little worse off than the day before! In the first 10 months of this year alone, an area the size of the Netherlands has been deforested and twice that area has been added to desert! Technology …

An architect’s research on a self-designed building: residential care facility for residents showing challenging behaviour. A seminar by Berit Ann RoosAs an architect I have designed a very intensive care (VIC) residential facility for intellectually impaired individuals showing challenging behavior. …

Background: Quality Improvement (QI) is the key for every healthcare organization. QI programs may help healthcare professionals to develop the needed skills for interprofessional collaboration through interprofessional education. Furthermore, the role of diversity in QI teams is not yet fully understood. …

The in 2000 established Water Framework Directive urges Member states to realize and maintain chemically clean and ecologically healthy water systems by 2027. Water Board Scheldestromen manages the water system of Zeeland which consists of mainly brackish waters. These types of waters have a variety …

Workers do not always showcase adequate knowledge on potential long-term health effects and other properties of particulate matter (PM), which may lead to a decreased tendency to work safely in a high-PM environment. To empower workers to work more safely in environments with high PM exposure, we developed …

Background: Only a few papers are published on the safety and effectiveness of acute burn care in low-income countries. A cohort study was therefore carried out to determine such outcomes. Methods: The study was conducted in a rural Tanzanian hospital in 2017-2018. All patients admitted with burns were …

Acne vulgaris is considered one of the most common medical skin conditions globally, affecting approximately 85% of individuals worldwide. While acne is most prevalent among adolescents between 15 to 24 years old, it is not uncommon in adults either. Acne addresses a number of different challenges, causing …