Health and social well-being depend on many contextual facets which are interdependent in a complex way and are all but limited to the field of cure and care. Publications of the World Health Organization and the Dutch Ministry of Health show that good health also depends on socioeconomic aspects such …

BACKGROUND: Frailty is associated with COVID-19 severity in clinical settings. No general population-based studies on the association between actual frailty status and COVID-19 hospitalization are available. AIMS: To investigate the association between frailty and the risk of COVID-19 hospitalization …

The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation might be attributed to differences in angiotensin-1 …

The 8 billionth citizen of the world will probably be born within a few months. Never before have we been on the planet with so many people at once. Of the 110 billion people who have lived since the dawn of humanity, 8/110 = 7.3% are present at the same time. Yet we are short of hands to do all the …

Campus Greensteel is the answer to the rehaul of the Tata Steel operations in IJmuiden. The change to hydrogen power restores the site as a natural dune area by the combination of architectural and biological strategies. After clearance of the coal and cokes depots and fossil powerplants, a network of …

Abstract Background: Approximately one-third of all patients with schizophrenia are treatment resistant. Worldwide, undertreatment with clozapine and other effective treatment options exist for people with treatment-resistant schizophrenia (TRS). In this respect, it appears that regular health care …

In the project 'Circular Wood for the Neighborhood', carried out by the Digital Production Research Group and partners, three cases were researched, each of them including prototyping. For case study 1, two small tables were designed and built from the wood of a front door.

In the project 'Circular Wood for the Neighborhood', carried out by the Digital Production Research Group and partners, three cases were research, each of the including prototyping. For case study 2, the prototypes focused on how to join a set of uneven pieces of wood. Two joints / nodes were designed …

Radio Kootwijk is a well-known architectural and historic icon near Apeldoorn, surrounded by extensive heath fields, sand dunes, and forests. Most of the old built infrastructure around it has disappeared, safe the ruins of Hotel Radio, a former workers pension. Benefiting from the natural environment …

Data, the raw material from which information is derived, is stored, copied, moved and modified more easily than ever. This quantum leap reaches levels outside our imagination. Surrounded by sensors, recommendation systems, invisible algorithms, spreadsheets and blockchains, the ‘difference that makes …