RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-function (LoF) variants in GRIN2B, resulting in dysfunction of the GluN2B subunit-containing N-methyl-d-aspartate receptor (NMDAR). Recently, in vitro experiments showed that …

Forensic DNA Trace Evidence Interpretation: Activity Level Propositions and Likelihood Ratios provides all foundational information required for a reader to understand the practice of evaluating forensic biology evidence given activity level propositions and to implement the practice into active casework …

This article presents and discusses an extracurricular, co-constructed programme: “The Catalyst Club” as a form of Artistic Educational Commoning (AEC). Having been developed as part of a PhD research at Minerva Art Academy (Groningen, The Netherlands), The Catalyst Club (TCC) explored new perspectives …

Laboratory experiments are important pedagogical tools in engineering courses. Restrictions related to the COVID-19 pandemic made it very difficult or impossible for laboratory classes to take place, resulting on a fast transition to simulation as an approach to guarantee the effectiveness of teaching. …

This research is conducted within the company context of Grosso Moda to investigate how the accuracy of digital garment simulation of suiting styles can be improved so that the product development process can replace physical samples with digital ones to improve efficiency while reducing time and costs. Suiting …

Background and objectives Before the Covid-19 pandemic, important social studies already indicated the severe negative feedback associated with high-rise developments. During the Covid-19 pandemic, citizens were confronted with their neighbourhoods’ insufficient restorative capacity to maintain their …

The aim of this research was to find out if Mycelium has the ability to replace stones in a roman arch bridge structure, by setting up the appropriate laboratory tests and by conducting a desk research to help identifying the best substrate out of the three substrates picked that will produce mycelium …

Wearable inertial sensors (WIS) facilitate the preservation of the athlete-environment relationship by allowing measurement outside the laboratory. WIS systems should be validated for team sports movements before they are used in sports performance and injury prevention research. The aim of the present …

Modifiable (biomechanical and neuromuscular) anterior cruciate ligament (ACL) injury risk factors have been identified in laboratory settings. These risk factors were subsequently used in ACL injury prevention measures. Due to the lack of ecological validity, the use of on-field data in the ACL injury …

This graduation report describes a research project at the research group metabolomics of the Leiden center of Applied Biosciences (LCAB). The aim of this project was to develop a GC-MS method for the identification of red swamp crayfish pheromones (Procambarus clarkii). Once this method has been developed, …