Purpose of review Serum or plasma citrulline levels are used as biomarker for a broad spectrum of intestinal functions. During high-dose chemotherapy, citrulline levels are decreased due to mucositis, a common side effect of chemotherapy. This may decrease intestinal function and result in diarrhea. …

Het eerste doel is het evalueren en verbeteren van machine learning algoritmes voor insulineadviezen voor jongeren met diabetes type 1. Het tweede doel is het ontwikkelen van een kennisbank met geanonimiseerde datasets ten behoeve van de opleiding HBO-ICT. Studenten kunnen hiermee praktijkervaring opdoen …

Introduction: In clinical practice AP pelvis standard protocols are suitable for average size patients. However, as the average body size has increased over the past decades, radiographers have had to improve their practice in order to ensure that adequate image quality with minimal radiation dose to …

INTRODUCTION: With the introduction of digital radiography, the feedback between image quality and over-exposure has been partly lost which in some cases has led to a steady increase in dose. Over the years the introduction of exposure index (EI) has been used to resolve this phenomenon referred to as …

Cervical dystonia (CD) is a neurological movement disorder characterized by involuntary muscle contractions causing abnormal postures and/or twisting movements of the head and neck. Patients may also experience non-motor symptoms including pain, anxiety and depression. The main treatment option is botulinum …

BACKGROUND: Acute kidney injury (AKI) often occurs in critically ill patients. AKI is associated with mortality and morbidity. Interventions focusing on the reduction of AKI are suggested by the Kidney Disease: Improving Global Outcomes guideline. We hypothesized that these educational interventions …

INTRODUCTION: In the Netherlands, Diagnostic Reference Levels (DRLs) have not been based on a national survey as proposed by ICRP. Instead, local exposure data, expert judgment and the international scientific literature were used as sources. This study investigated whether the current DRLs are reasonable …

Door recente verlaging van de equivalente dosis van de ooglens van 150 mSv naar 20 mSv per jaar, is het belang van goed monitoren van ontvangen dosis nog belangrijker geworden. In deze studie is onderzocht wat de stralenbelasting is van interventiecardiologen, cardio-thoracaalchirurg, cardio-anesthesiologen …

Het doel van dit onderzoek is om te identificeren welke factoren invloed hebben op het gewichtsverlies tijdens de chemoradiatie van patiënten met NSCLC-stadium III. Door deze factoren te bepalen, kan hier mogelijk preventief op worden ingespeeld tijdens het behandelproces. Van de NSCLC-stadium III patiënten …

Development of novel testing strategies to detect adverse human health effects is of interest to replace in vivo-based drug and chemical safety testing. The aim of the present study was to investigate whether physiologically based kinetic (PBK) modeling-facilitated conversion of in vitro toxicity data …