5% to 10% of all cancers are linked to gene mutations inherited from parents. The most common gene related to hereditary cancer is the p53 gene. It is a crucial tumor suppressor. However, the mutated gene is commonly inherited from one generation to another one. The functions of p53 resume to the activation …

Nowadays, one of the major current health risks is excessive sitting during work hours. Furthermore, the coronavirus disease 2019 (COVID-19) pandemic and the corresponding government state of emergency forced many people to work from home. These constraints carried out an important change in the lifestyle …

Balance deficits play a major role in patients who have suffered strokes. It is estimated that 30% of patients cannot walk independently 6 months post-stroke, usually caused by impaired standing balance due to hemiplegia or hemiparesis that is experienced. Balance as a whole is a key factor when it comes …

Aims Genetic hypertrophic cardiomyopathy (HCM) is caused by mutations in sarcomere protein-encoding genes (i.e. genotype-positive HCM). In an increasing number of patients, HCM occurs in the absence of a mutation (i.e. genotype-negative HCM). Mitochondrial dysfunction is thought to be a key driver of …

Movement disorders in dementia are not well known yet they have a devastating effect on the quality of life and the abilities of a person with dementia. Paratonia is one of these movement disorders that are already present in 10% of the population with dementia in the early stages and increase up to …

There is an increasing interest in how to create an effective and comfortable indoor environment for lecturers and students in higher education. To achieve evidence-based improvements in the indoor environmental quality (IEQ) of higher education learning environments, this research aimed to gain new …

After reopening in March 2022 Sir Adam Hotel has been dealing with a declining guest satisfaction rate of 5,6% while providing the same guest experience. Studies have shown that this is caused by the increase of negative psychological effects which are caused by COVID-19. Resulting in complained behavior …

Purpose: This study aims to qualitatively examine the relationship between the indoor environmental quality (IEQ), lecturers’ and students’ perceived internal responses and academic performance. Design/methodology/approach: To capture user experiences with the IEQ in classrooms, semi-structured interviews …

The growing sophistication, frequency and severity of cyberattacks targeting all sectors highlight their inevitability and the impossibility of completely protecting the integrity of critical computer systems. In this context, cyber-resilience offers an attractive alternative to the existing cybersecurity …

Despite the inherent conservatism of the hospitality industry, times are changing and challenges are arising in the workforce. Staff shortages in hospitality organisations in the Netherlands are severely caused by a great resignation from hospitality employment. Research suggests that a significant antecedent …