Summary: Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate these pathway predictions. The Xpaths algorithms are applied …

This paper aims to address the research gap in ethical design frameworks for self-sovereign identity (SSI) solutions. We present a case study of value sensitive design (VSD) conceptual investigation applied in the context of SSI-based solutions for the sharing of medical credentials uNLock. We evaluate …

Given the hospitality industry's quick rebound and volume growth in most OECD nations following the Great Recession, the hotel sector in the Netherlands is currently experiencing a severe labour shortage that predates the Covid-19 epidemic (Joppe, 2012). Staff shortages and cost-cutting measures in the …

Changes, challenges and expectations of society call for ongoing professional development of teachers. However, in many schools ongoing professional development cannot be taken for granted. Many governmental, local or institutional policies aim at stimulating teachers’ professional development, but many …

With the proliferation of misinformation on the web, automatic methods for detecting misinformation are becoming an increasingly important subject of study. If automatic misinformation detection is applied in a real-world setting, it is necessary to validate the methods being used. Large language models …

With the world facing an ecological crisis, Hindus are challenged to reflect on the ways they impact their environment. The last few decades witnessed a rise of theological reflections on Hindu traditions—especially scriptures and concepts (not least by western scholars)—that advocate environmentally …

Study design Cross-sectional study. Objectives The aims of this study were (1) to validate the two recently developed SCI-specific REE equations; (2) to develop new prediction equations to predict REE in a general population with SCI. Setting University, the Netherlands. Methods Forty-eight community-dwelling …

Drug consumption estimates are of relevance because of public health effects as well as associated criminal activities. Wastewater analysis of drug residues enables the estimation of drug consumption and drug markets. Short-term and long-term trends of cocaine, MDMA (ecstasy), amphetamine (speed) and …

Background While low back pain occurs in nearly everybody and is the leading cause of disability worldwide, we lack instruments to accurately predict persistence of acute low back pain. We aimed to develop and internally validate a machine learning model predicting non-recovery in acute low back pain …

Presentatie over terugblik en ambities van innovatiewerkplaats Healthy Workplace