Nutrition is one of the modifiable risk factors for cognitive decline and Alzheimer's disease (AD) dementia, and is therefore highly relevant in the context of prevention. However, knowledge of dietary quality in clinical populations on the spectrum of AD dementia is lacking, therefore we studied the …

Background: To investigate trends over age by comorbidity status for the risk of limitations in individual activities of daily living for community-living older persons.Methods: A longitudinal population-based study was conducted in 9,319 community-living Dutch persons …

Abstract Background An increasing number of the ageing population worldwide is at risk of becoming frail and incapacitated. This has the potential to impact not only on the well-being of individuals but also on the sustainability of healthcare systems. Objective The aim of this study was to explore …

Population decline, welfare state reforms and austerity measures pressurise the liveability of rural areas in the Netherlands and call upon local governments and communities to adapt and renew their mode of governance. This paper reports on three Dutch experimental governance arrangements which are analysed …

Frailty, a complex phenomenon The population worldwide is ageing rapidly and with age an increase in co-morbidities and a decline in abilities is seen. Frailty is an often-used term to indicate a higher risk to adverse health outcomes. The often used definition of Fried et al 2001 is clinically driven …

The Northern region of the Netherlands has beautiful landscapes, a nice diversity of green and blue areas, and dispersed settlements. However, some recent population changes can become threats to health and wellbeing in these areas. The rural areas in the three northern provinces - Groningen, Friesland …

Due to closure of the coal mines industry in Heerlen lots of people lost their jobs and decided to leave Heerlen. The decline of population and economy resulted in a lot of vacant housing and retail. Through a minimalistic architecture this project syncs the upcycling of plastic with new efforts of the …

Background: This study investigated the trajectories of decline in individual instrumental activities of daily living (IADL) with aging and the effect of hearing loss, vision loss, or dual sensory loss on these trajectories in community-living frail older persons. Method: This longitudinal population-based …

Background: Decline in physical activity and functioning is commonly observed in the older population and might be associated with biomarkers such as Advanced Glycation End-products (AGEs). AGEs contribute to age-related decline in the function of cells and tissues in normal aging and have been found …

What is essential when trying to stimulate / preserve vitallity in regions confronted with ageing and unbalanced population decline?