OBJECTIVES: To explore the feasibility of a newly developed model of stratified exercise therapy in primary care for patients with knee osteoarthritis (OA). DESIGN: Mixed method design (process, outcome and qualitative evaluation). SETTING: Six physical therapy practices in primary care around Amsterdam. …

Designing privacy-protecting Information Systems (ISs), i.e., realizing the Privacy by Design (PbD) principle, is a challenging task. This challenge stems from having many stakeholders and design trade-offs involved, which cause uncertainty in defining the problem, eliciting soft requirements, and making …

Objectives: To determine the psychometric properties of a questionnaire to assess fear of movement (kinesiophobia): the Tampa Scale for Kinesiophobia (TSK-NL Heart), and to investigate the prevalence of kinesiophobia in patients attending cardiac rehabilitation. Methods: A total of 152 patients were …

Background Early detection of frail older people is important. Timely intervention may allow health care professionals to prevent or delay the occurrence of adverse outcomes such as disability, increases in health care utilization, and premature death. Objectives We assessed the construct and criterion …

Background There is little focus on adults with cerebral palsy (CP) in research and health care and insufficient knowledge on how to identify and manage pain in this population. Objectives This systematic review and meta-analysis aimed to determine whether pain prevalence in adults with CP is high …

At present, leading international agencies, such as the United Nations Environmental Programme, are largely focused on what they claim to be ‘win-win’ scenarios of ‘sustainable development’ rhetoric. These combine social, economic and environmental objectives. However, as noted by the ‘Scientists’ Warning …

To support the implementation of the Ecosystem Based approach to Management (EBM), ICES strives to provide evidence-based scientific advice and relevant management options that also assess potential trade-offs among sectors or between environmental status and human uses. To help achieve this, the Workshop …

BACKGROUND: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an unpredictable pharmacokinetic/pharmacodynamic profile. Conventional intermittent …

Increased spatial pressures on the marine environment asks for smart use of space in order to safeguard the achievement of environmental, social and economic objectives. Multi-use is seen as a new paradigm for space efficiency and might yield other benefits beyond that. Within the scope of their Policy …

Background: The increasing numbers of surgeries involving high risk, multi-morbid patients, coupled with inconsistencies in the practice of perioperative surgical wound care, increases patients’ risk of surgical site infection and other wound complications. Objectives: To synthesise and evaluate the …