The architecture of TP 53 , the most frequently mutated gene in human cancer, is more complex than previously thought. Using TP 53 variants as clinical biomarkers to predict response to treatment or patient outcome requires an unequivocal and standardized procedure toward a definitive strategy for the …

Knowledge workers share two basic needs: their productivity requires isolation (internalization of knowledge) and interaction (externalization of knowledge), supported by different spatial concepts. None of the work environments involved in the study adequately support all of the phases in the knowledge …

Clusters development takes place in an increasingly changing and complex context where global and local developments are interconnected. Various regional and innovation studies recognize the need for place-based studies to include the larger context in which clusters and regions are found. Interest and …

Life-cycle costing (LCC), originally developed by the US DoD, promises integrated insight in investment, maintenance, usage and disposal costs of weapon systems. In an era of tightening budgets, these opportunities have led to programs to tailor and implement LCC. At present, conceptual development of …

Internationalizing curricula. Needs and wishes of alumni and employers with regard to international competencies. Internationalization has become of great importance for universities acrossthe globe. The labour market is becoming international, with internationalopportunities and international competition. …

Purpose - This paper aims to identify whether employees’ organisational position affect their perceived quality of the workspace design. By providing possible explanations for the differences and discussing the implications, we aim to establish an effective workspace design process that satisfies different …

In response to demographic changes in the Netherlands, schools in the Dutch higher education sector aim to develop and implement diversity policies and interventions to increase the representation of ethnic minorities in the work place. How can such a structural movement for diversity development within …

This report describes the work that has been done on the water calorimeter project at VSL. The calorimeter determines the absorbed-dose-to water Dw in gray, by measuring the radiation induced temperature change. The temperature of the water will change due to irradiation of a beam ionizing radiation. …

Purpose: The purpose of this paper is to focus on the effects of career development and guidance among students (age 17-23) enrolled in higher education in The Netherlands. First the paper explores whether the development of career competencies contribute to career identity, learning motivation, certainty …

Many companies have included social media features in their corporate intranets to encourage collaboration and knowledge sharing, and to improve internal communications. Since November 2013 Rabobank International(RI) has launched their new worldwide social intranet, Meeting point. However, like in many …