The case we describe is the journey of one company, a SME sheet metal manufacturing company in development of a Digital Twin in a production setting. We choose to highlight this specific case for several reasons: • A clear Industry 40 technology was the center piece of the project: The development of …

Although much research has been done into the importance of IT Capabilities (ITC), Digital Leadership (DL) and Digital Transformation (DT) with regard to organizations’ firm performance and ability to thrive in the current digital market, there is little research on qualifying which specific ITC and …

BACKGROUND: Since the benefit-harm balance of adding inhaled corticosteroids to long-acting β2-agonists (LABA) and long-acting muscarinic antagonists (LAMA) for patients with chronic obstructive pulmonary disease is unclear, we evaluated this addition for a range of patient profiles. METHODS: Analyses …

Background Understanding the kinematic characteristics of relapse clubfoot compared to successfully treated clubfoot could aid early identification of a relapse and improve treatment planning. The usage of a multi segment foot model is essential in order to grasp the full complexity of the multi-planar …

BACKGROUND: As the number of cancer survivors is increasing, it is important to be able to offer exercise and physical activity (PA)-promoting interventions that are both effective and reasonably accessible. Internet-based interventions are typically less expensive and more accessible alternatives to …

Urban experimentation has been increasingly applied as an urban development tool for finding new ways to face grand societal challenges, as they unfold in cities⁠. Experiments might trigger systemic change, since they differ conceptually from conventional urban development, as they can be radical in …

Fashion is under scrutiny. Social activists raise the debate around animal welfare in the apparel industry. With shocking and disturbing images, they are campaigning to attract worldwide media attention in order to highlight serious animal abuse in production of fashion, and influence consumption. Our …

The aging process is often accompanied by increase in body weight. Older adults with overweight or obesity might have an overconsumption in energy that is accompanied by inadequate intake of protein, vitamin D, and calcium. It is unclear if intake of protein and vitamin D and calcium is sufficient in …

Background Physical exercise is an intervention that might protect against doxorubicin‐induced cardiotoxicity. In this meta‐analysis and systematic review, we aimed to estimate the effect of exercise on doxorubicin‐induced cardiotoxicity and to evaluate mechanisms underlying exercise‐mediated cardioprotection …

Organizations operate in a socio-economic context, and alignment with this context is key for business success. The rate of change and impact of these changes on the operating model of the organization appears to be increasing. Major trends are the aftermath of the financial crisis of 2008, the “VUCA” …