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Generating & characterizing pathogenic KCNH2 variants in hiPSCs to study LQT2 syndrome

Nini Schotman (Student)

Generating & characterizing pathogenic KCNH2 variants in hiPSCs to study LQT2 syndrome

2023-06-13GezondheidBachelor

Eindcriteria bij het post-covid syndroom behandeltraject: opinies uit de eerste lijn.

Sem Weert (Student)

Post Covid Syndroom (PCS) is de term voor langdurig aanhoudende coronaklachten. Deze klachten bestaan hoofdzakelijk uit vermoeidheid, spierzwakte, mentale klachten en cognitieve problematiek. Omdat er nog veel onduidelijk is over PCS is het ook niet duidelijk hoe deze patiënten moeten worden behandeld, …

2023-06-11GezondheidBachelor

Lung Ultrasound to Determine the Effect of Lower vs. Higher PEEP on Lung Aeration in Patients without ARDS—A Substudy of a Randomized Clinical Trial

Zimatore, Claudio; Algera, Anna Geke; Botta, Michela; Pierrakos, Charalampos; Serpa Neto, Ary; Grasso, Salvatore; Schultz, Marcus J.; Pisani, Luigi; Paulus, Frederique (Lectoraat Critical Care)

Background: Ventilation with lower positive end–expiratory pressure (PEEP) may cause loss of lung aeration in critically ill invasively ventilated patients. This study investigated whether a systematic lung ultrasound (LUS) scoring system can detect such changes in lung aeration in a study comparing …

2023-06AlgemeenArtikel

Importance analysis of psychosociological variables in frailty syndrome in heart failure patients using machine learning approach

Aleksandra H. Pasieczna; Remigiusz Szczepanowski; Janusz Sobecki; Radosław Katarzyniak; Izabella Uchmanowicz; Robbert Gobbens (Lector); Aleksander Kahsin (Begeleider); Anant Dixit

The prevention and diagnosis of frailty syndrome (FS) in cardiac patients requires innovative systems to support medical personnel, patient adherence, and self-care behavior. To do so, modern medicine uses a supervised machine learning approach (ML) to study the psychosocial domains of frailty in cardiac …

2023-05-15GezondheidArtikel

De nurse-led GILL e-health interventie voor somatische screening en leefstijlbevordering bij mensen met een ernstige psychiatrische aandoening

Meike Hoogervorst (Lid Lectoraat); Esther Krijnen-de Bruin (Lid Lectoraat); N. Boonstra; Marcel C. Adriaanse; Berno van Meijel (Lector)

SAMENVATTING Mensen met een ernstige psychiatrische aandoening (EPA) hebben een sterk verminderde levensver wachting in vergelijking met de algemene populatie, vooral veroorzaakt door fysieke aandoeningen. Een ongezonde leefstijl speelt een belangrijke rol in de verminderde levensverwachting bij mensen …

2023-04-26GezondheidArtikel

Hereditary Cancer

Cezara Balatel (Student); Anne von Bergh (Lector)

5% to 10% of all cancers are linked to gene mutations inherited from parents. The most common gene related to hereditary cancer is the p53 gene. It is a crucial tumor suppressor. However, the mutated gene is commonly inherited from one generation to another one. The functions of p53 resume to the activation …

2023-04-20Gezondheid; …Bachelor

An exploratory study of clinical characteristics and gait features of adolescents with hypermobility disorders

de Koning, Lisanne E. (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); Scheper, Mark C.; Ploeger, Hilde E.; Warnink-Kavelaars, Jessica; Oosterlaan, Jaap; Bus, Sicco A.; Engelbert, Raoul H.H. (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten)

Background In adolescents with non-pathological and pathological joint hypermobility, gait deviations have been associated with pain and fatigue. It remains unclear what distinguishes the non-pathological form of joint hypermobility (JH) from pathological forms (i.e. hypermobile Ehlers-Danlos syndrome …

2023-02AlgemeenArtikel

Effect of mechanical power on mortality in invasively ventilated ICU patients without the acute respiratory distress syndrome

van Meenen, David M.P.; Algera, Anna Geke; Schuijt, Michiel T.U.; Simonis, Fabienne D.; van der Hoeven, Sophia M.; Neto, Ary Serpa; Abreu, Marcelo Gama de; Pelosi, Paolo; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

BACKGROUND The mechanical power of ventilation (MP) has an association with outcome in invasively ventilated patients with the acute respiratory distress syndrome (ARDS). Whether a similar association exists in invasively ventilated patients without ARDS is less certain. OBJECTIVE To investigate the …

2023-01AlgemeenArtikel

Patients with and without COVID-19 in the Intensive Care Unit: Physical Status Outcome Comparisons 3 Months after Discharge

Bas Cijs (Onderzoeker); Karin Valkenet (Onderzoeker); Germijn Heijnen (Onderzoeker); Anne Visser‑Meily (Onderzoeker); Marike van der Schaaf (Onderzoeker)

Objective: Many patients with COVID-19 infections were admitted to an intensive care unit (ICU). Physical impairments are common after ICU stays and are associated with clinical and patient characteristics. To date, it is unknown if physical functioning and health status are comparable between patients …

2023GezondheidArtikel

Application of Axiomatic Design in Engineering: Designing a Smart Medical Cast

Tim Heijne (Onderzoeker); Mitch Kruijer (Onderzoeker); Jakub Kylar (Onderzoeker); Lennard Spauwen (Onderzoeker); Karin Thomassen (Onderzoeker); Erik Puik (Onderzoeker)

By applying Axiomatic Design, a Smart Medical Cast was developed to provide patients, who are suffering from forearm fractures, with a personalized healing process. The device monitors the overall healing status and three complications, which are: Muscle Atrophy, Compartment Syndrome, and Deep Vein Thrombosis. …

2023GezondheidConferentiebijdrage

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