The simultaneous analysis of a broad range of polar ionogenic metabolites using capillary electrophoresis-mass spectrometry (CE-MS) can be challenging, as two different analytical methods are often required, that is, one for cations and one for anions. Even though CE-MS has shown to be an effective method …

BACKGROUND: Since the benefit-harm balance of adding inhaled corticosteroids to long-acting β2-agonists (LABA) and long-acting muscarinic antagonists (LAMA) for patients with chronic obstructive pulmonary disease is unclear, we evaluated this addition for a range of patient profiles. METHODS: Analyses …

Background: Ecstasy (3,4-methylenedioxymethamphetamine (MDMA)) has a relatively low harm and low dependence liability but is scheduled on List I of the Dutch Opium Act (‘hard drugs’). Concerns surrounding increasing MDMA-related criminality coupled with the possibly inappropriate scheduling of MDMA initiated …

Abstract Background Patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are treated with supplemental oxygen, but the benefits and harms of different oxygenation targ...

This white paper is presented by the Ethics Working Group of the uNLock Consortium This white paper presents findings of the Ethics Working Group, from the conceptual phase of investigation into the ethical issues of the uNLock solution, providing identity management solutions for sharing and presentation …

Plastic is one of the most popular materials used in products, but it also leaves the earth to deal with a major environmental issue, namely plastic pollution. The oceans in particular are filled with plastic waste, which harms biodiversity and ecosystems. It also negatively impacts countries and their …

Bijdrage gepresenteerd op de Landelijke Werkconferentie Platform Taalgericht Vakonderwijs Berghotel, 6 december 2019

Abstract: Self-harming behavior: complex, but recovery is possible Self-harming behavior among adolescents is an alarming phenomenon: it is a sign of underlying suffering and not knowing how to handle this. Often, there are intense and overwhelming emotions which are unbearable for these patients, …

On May 20, 2016, the Member States of the European Union will have to transpose the 2014/40/EU revised tobacco directive. The dissertation in front of you provides an understanding of the revised tobacco directive and the transposition of the directive into North Rhine-Westphalian law. The historical, …