Hereditary Breast and Ovarian Cancer (HBOC) typically arises from mutations inherited in the germline. BRCA1 and BRCA2 mutaions are predominant contributors to HBOC, accounting for the majority of cases. These mutations are associated with 10% of ovarian cancer cases and 3-5% of breast cancer cases [4]. BRCA1 …

Introduction: Self-regulated learning (SRL) has traditionally been associated with study success in higher education. In contrast, study success is still rarely associated with executive functions (EF), while it is known from neuropsychological practice that EF can influence overall functioning and performance. …

Introduction: Self-regulated learning (SRL) has traditionally been associated with study success in higher education. In contrast, study success is still rarely associated with executive functions (EF), while it is known from neuropsychological practice that EF can influence overall functioning and performance. …

Background: The concept of “positive health” emerged from the need for a holistic and more dynamic perspective on health, emphasising the ability of individuals to adapt and self-manage. The positive health conversation tool helps understand how people score on six positive health dimensions. However, …

The purpose of this paper is to discuss the insights gained by testing in a design studio a particular research-by-design strategy, focusing on the generation of innovative solutions for climate change adaptation. The strategy is based on the Design Thinking Process and has been applied in the climate …

Western cities are rapidly densifying, and new building typologies are being invented to mitigate high-rise and balance residential, commercial and recreational functions. This vertical urbanization requires rethinking the traditional design of public space to promote citizens’ well-being. While the …

Tumor necrosis factor alpha (TNF-α) and its key role in modulating immune responses has been widely recognized as a therapeutic target for inflammatory and neurodegenerative diseases. Even though inhibition of TNF-α is beneficial for the treatment of certain inflammatory diseases, total neutralization …

Reuse and transformation of industrial heritage is intricately linked to history, context, and architectural debate. In a critical process of theoretical research and research-by-design, a case is built up around the former water tower on one of the riverbanks in Wroclaw, Poland. The solid construction …

Hof van den Houte’ is the new name for a shopping and housing district in the present heart of Etten-Leur, once the site of a castle by the same name between the villages Etten and Leur. The site was still an open field when a modern freestanding shopping mall was built in the 1960s to serve the growing …

The Silestra Museum Forum is part of an intended strategy to reboot cultural and social life in the city by enhancing neglected historical sites and public spaces with new cultural and social functions. This new connective network makes clever use of the old city fabric, including the park bordering …