Voor veel jongeren in het hoger onderwijs (hbo en wo) is de studententijd een periode waarin regelmatig (veel) alcohol wordt gedronken. Daarnaast komt er in deze fase ook vaak voor het eerst drugsgebruik ter sprake (Trimbos-instituut, 2021). Dit middelengebruik brengt verscheidene risico’s met zich mee. …

Door middel van een praktijkgericht kwalitatief onderzoek is gekeken naar de feitelijke en gewenste situatie omtrent de toenemende lachgasproblematiek en delinquent gedrag binnen reclasseringstrajecten van GGZ Reclassering Fivoor. Om een zo compleet mogelijk beeld hierover te krijgen heeft er literatuur- …

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Drug consumption estimates are of relevance because of public health effects as well as associated criminal activities. Wastewater analysis of drug residues enables the estimation of drug consumption and drug markets. Short-term and long-term trends of cocaine, MDMA (ecstasy), amphetamine (speed) and …

Cannabis is commonly characterized as the most normalized illicit drug. However, it remains a prohibited substance in most parts of the world, including Europe, and users can still be subject to stigmatization. The objective of this study is to assess to what extent and how cannabis users in different …

The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation might be attributed to differences in angiotensin-1 …

The aim of this cross-sectional study is (1) to describe the socio-demographic characteristics of students with relatives with problematic substance use and to examine differences between students with and without relatives with problematic substance use in (2) health, (3) substance use and (4) study …

New approach methodologies predicting human cardiotoxicity are of interest to support or even replace in vivo-based drug safety testing. The present study presents an in vitro–in silico approach to predict the effect of inter-individual and inter-ethnic kinetic variations in the cardiotoxicity of R- …

ABSTRACT Background: We investigated if the addition of an inter-professional student-led medication review team (ISP-team) to standard care can increase the number of detected ADRs and reduce the number of ADRs 3 months after an outpatient visit. Research design and methods: In this controlled clinical …