Background & aims:  Low muscle mass and -quality on ICU admission, as assessed by muscle area and -density on CT-scanning at lumbar level 3 (L3), are associated with increased mortality. However, CT-scan analysis is not feasible for standard care. Bioelectrical impedance analysis (BIA) assesses body …

BACKGROUND: The number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. Sepsis incidence has risen in recent years and identification of outcomes is of considerable …

Development of novel testing strategies to detect adverse human health effects is of interest to replace in vivo-based drug and chemical safety testing. The aim of the present study was to investigate whether physiologically based kinetic (PBK) modeling-facilitated conversion of in vitro toxicity data …

Objective: The Tilburg Frailty Indicator (TFI) is a self-report user-friendly questionnaire for assessing multidimensional frailty among community-dwelling older people. The main aim of this study is to re-evaluate the validity of the TFI, both cross-sectionally and longitudinally, focusing on the predictive …

During this research project the influence of selenium enriched growing environment on the phenolic composition on several Allium species is studied. Besides this, the influence on morphological properties is also monitored. Folin-Ciocalteu method is used to determine the total phenolic content and High …

The aim of this study was to assess the predictive ability of the frailty phenotype (FP), Groningen Frailty Indicator (GFI), Tilburg Frailty Indicator (TFI) and frailty index (FI) for the outcomes mortality, hospitalization and increase in dependency in (instrumental) activities of daily living ((I)ADL) …

Energy dissipative steel cushions (EDSCs) are simple units that can be used to join structural members. They can absorb a substantial amount of seismic energy due to their geometric shapes and the ductile behavior of mild steel. Large deformation capability and stable hysteretic behavior were obtained …

Lasiocarpine and riddelliine are pyrrolizidine alkaloids (PAs) known to cause liver toxicity. The aim of this study was to predict the inter-species and inter-ethnic human differences in acute liver toxicity of lasiocarpine and riddelliine using physiologically based kinetic (PBK) modelling based reverse …

Sarajevo is a stratification of urban, historical and cultural diversities. The goal of this project is to unfold and visualize history through the power of Architecture. The historic landscapes of Sarajevo is a manifesto of the city, tribute to its variegated history an invitation to travel through …

Sarajevo is a stratification of urban, historical and cultural diversities. The goal of this project is to unfold and visualize history through the power of Architecture. The historic landscapes of Sarajevo is a manifesto of the city, tribute to its variegated history an invitation to travel through …