Background: Early childhood caries is considered one of the most prevalent diseases in childhood, affecting almost half of preschool-age children globally. In the Netherlands, approximately one-third of children aged 5 years already have dental caries, and dental care providers experience problems reaching …

Infectious diseases are a severe threat to human health. We believe that smartphones may be used as a valuable non-pharmaceutical tool to fight epidemics. We designed and evaluated the capability to fight epidemics with smartphones. This is the abstract of one of the oral presentations of the International …

Background We aimed to identify healthcare needs, expectations, utilization, and the experienced treatment effects in a population of Dutch patients with hereditary spastic paraplegia (HSP). Methods We distributed an online questionnaire among 194 adult persons with HSP in the Netherlands, of which 166 …

Proefschrift van Janneke Scheerman: Fixed orthodontic treatment Orthodontics is the branch of dentistry concerned with facial growth and the development of the dentition, and with occlusion and the prevention and correction of occlusal anomalies [1]. Approximately 53-57% of Dutch 12-year olds undergo …

OBJECTIVE: Periodontitis, mostly associated with Porphyromonas gingivalis, has frequently been related to adverse pregnancy outcomes. We therefore investigated whether lipopolysaccharides of P. gingivalis (Pg-LPS) induced pregnancy complications in the rat. METHODS: Experiment 1: pregnant rats (day 14) …

OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with …