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Changes in inflammation and musculoskeletal tissue-derived biomarker serum levels in response to high- and low-intensity resistance training in individuals with knee osteoarthritis

Jansen, N.E.; Engstrøm, A.; Thudium, C.S.; Bay-Jensen, A-C.; de Zwart, A.H.; Dekker, J.; Lems, W.F.; Gerritsen, M.; van Spil, W.E.; Jaspers, R.T.; Turkstra, F.; van der Leeden, M.; van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

Purpose: Exercise therapy with a focus on muscle strengthening has proven to be effective for the management of knee osteoarthritis (OA). Yet it is not known whether high-intensity resistance training (RT) is more effective in improving upper leg muscle strength and physical performance than low-intensity …

2020-04AlgemeenArtikel

The effect of perceived knee joint instability on responses to external perturbations during gait in patients with knee osteoarthritis

Schrijvers, J.; van den Noort, J.; van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen); Harlaar, J.

Purpose: Instability of the knee joint is reported by a majority (>65%) of patients with knee osteoarthritis (KOA) and is hypothesized to play a crucial role in the initiation and progression of KOA. A generally accepted objective metric of knee joint stability is lacking, making development of diagnostics …

2020-04AlgemeenArtikel

A consensus-based framework for conducting and reporting osteoarthritis phenotype research

van Spil, W. E.; Bierma-Zeinstra, S. M. A.; Deveza, L. A.; Arden, N. K.; Bay-Jensen, A.-C.; Kraus, V. Byers; Carlesso, L.; Christensen, R.; Van Der Esch, M. (Centre Of Expertise Urban Vitality); Kent, P.; Knoop, J.; Ladel, C.; Little, C. B.; Loeser, R. F.; Losina, E.; Mills, K.; Mobasheri, A.; Nelson, A. E.; Neogi, T.; Peat, G. M.; Rat, A.-C.; Steultjens, M.; Thomas, M. J.; Valdes, A. M.; Hunter, D. J.

BACKGROUND: The concept of osteoarthritis (OA) heterogeneity is evolving and gaining renewed interest. According to this concept, distinct subtypes of OA need to be defined that will likely require recognition in research design and different approaches to clinical management. Although seemingly plausible, …

2020-03-20AlgemeenArtikel

Is a model of stratified exercise therapy by physical therapists in primary care feasible in patients with knee osteoarthritis?

Knoop, J.; van der Leeden, M.; van der Esch, M. (Centre Of Expertise Urban Vitality); de Rooij, M.; Peter, W.F.; Bennell, K.L.; Steultjens, P.M.; Hakkinen, A.; Roorda, L.D.; Lems, W.F.; Dekker, J.

OBJECTIVES: To explore the feasibility of a newly developed model of stratified exercise therapy in primary care for patients with knee osteoarthritis (OA). DESIGN: Mixed method design (process, outcome and qualitative evaluation). SETTING: Six physical therapy practices in primary care around Amsterdam. …

2020-03AlgemeenArtikel

Development of a core capability framework for qualified health professionals to optimise care for people with osteoarthritis: an OARSI initiative

Hinman, R.S.; Allen, K.D.; Bennell, K.L.; Berenbaum, F.; Betteridge, N.; Briggs, A.M.; Campbell, P.K.; Dahlberg, L.E.; Dziedzic, K.S.; Eyles, J.P.; Hunter, D.J.; Skou, S.T.; Woolf, A.; Yu, S P; van der Esch, M (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

OBJECTIVE: Develop a generic trans-disciplinary, skills-based capability framework for health professionals providing care for people with OA. DESIGN: e-Delphi survey. An international inter-professional Delphi Panel (researchers; clinicians; consumer representatives) considered a draft framework (adapted …

2020-02AlgemeenArtikel

Is a model of stratified exercise therapy by physical therapists in primary care feasible in patients with knee osteoarthritis? : a mixed methods study.

J. Knoop; M van der Leeden; M. van der Esch; M. de Rooij; W.F. Peter; K.L. Bennell; M.P.M. Steultjens; A. Hakkinen; L.D. Roorda; W.F. Lems; J Dekker

2020AlgemeenArtikel

The association between physical activity and cardiorespiratory fitness in patients with rheumatoid artahrtis and high cardiovascular risk

Van den Hoek, J. (Hogeschool Van Amsterdam); Van der Leeden, M.; Metsios, G.; Kitas, G.; Jorstad, H.; Lems, W.; Nurmohamed, M.; Van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

Background: Rheumatoid arthritis (RA) is associated with increased risk of cardiovascular disease (CVD) disease and CV mortality1. High values of cardiorespiratory fitness (CRF) are protective against CVD and CV mortality2. Physical activity levels in patients with RA are low. Knowledge on whether physical …

2020AlgemeenArtikel

Knee osteoarthritis and comorbidity

de Rooij, M; van der Leeden, M.; van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen); Lems, W.F.; Meesters, J; Roorda, L.D.; Terbraak, M.; Vredeveld, T.; Vliet Vlieland, T.P.; Dekker, J.

Purpose : A structured, tailored exercise therapy strategy was found to significantly improve physical functioning, reduce pain and was safe for patients with knee osteoarthritis (OA) and severe comorbidity. The intervention was performed in a specialized, secondary care center. Before the intervention …

2018-04AlgemeenArtikel

Hip fractures in older patients

Aarden, J.J. (Faculteit Gezondheid); van der Esch, M.; Engelbert, R.H.H.; van der Schaaf, M. (Faculteit Gezondheid); de Rooij, S.E.; Buurman, B.M.

Abstract: Background: Hip fracture in older patients often lead to permanent disabilities and can result in mortality. Objective: To identify distinct disability trajectories from admission to one-year post-discharge in acutely hospitalized older patients after hip fracture. Design: Prospective cohort …

2017AlgemeenArtikel

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