Lasiocarpine and riddelliine are pyrrolizidine alkaloids (PAs) known to cause liver toxicity. The aim of this study was to predict the inter-species and inter-ethnic human differences in acute liver toxicity of lasiocarpine and riddelliine using physiologically based kinetic (PBK) modelling based reverse …

Background: Patient decision aids (PDAs) can support the treatment decision making process and empower patients to take a proactive role in their treatment pathway while using a shared decision-making (SDM) approach making participatory medicine possible. The aim of this study was to develop a PDA for …

The case study assesses the question ‘how can Scope best utilise the critical success factors of Scope One to gain market share?’, by focusing on identifying and analysing the critical success factors of Scope One. A framework was devised from four project management theories and two agile software development …

Mexican oregano is a non-timber forest product harvested in natural vegetation and represents an important source of income for rural families. Recent reports have highlighted decreases in natural populations caused by increased harvest intensity. Oregano leaf harvesting is a complex problem, involving …

Climate change has caused dilapidation of the environment, droughts and floods leading to reduced yields, productivity and ultimately food insecurity for human consumption. Unfortunately, it is our contact with the environment that has led to all this, but most people are not aware. The three gases contributing …

The current assignment of vocational programs in higher education is to educate future evidence-based professionals. Often is presumed that a substantial connection between research and teaching is needed to be able to provide the right context and content to achieve this aim with students (Healey & …

Background: Integrating physical therapy sessions and an online application (e-Exercise) might support people with hip osteoarthritis (OA), knee OA, or both (hip/knee OA) in taking an active role in the management of their chronic condition and may reduce the number of physical therapy sessions. Objective: …

Motor learning is particularly challenging in neurological rehabilitation: patients who suffer from neurological diseases experience both physical limitations and difficulties of cognition and communication that affect and/or complicate the motor learning process. Therapists (e.g.,, physiotherapists …

Prolonged sitting time in adults has become a major societal issue with far-reaching health, economic, and social consequences. The objective of this study is to reduce sedentary behaviour in office workers by integrating physical activity with work. In this case study, we present Workwalk, a concept …