This monograph describes many applications of peroxidase-based biocatalysis in the biotechnology industry. The need for such a book emerges from the considerable amount of new data regarding the phylogeny, reaction mechanisms, thermodynamic characterization and structural features of fungal and plant …

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Introduction: To reduce continuously increasing costs in drug development, adverse effects of drugs need to be detected as early as possible in the process. In recent years, compound-induced gene expression profiling methodologies have been developed to assess compound toxicity, including Gene Ontology …

The extent to which action research has a democratising influence - and the ethical pitfalls involved in the practice of action research. The conduct of action research within the organisational context and the practice community receives attention.

IL-4 and IL-13 are prototypic Th2 cytokines that generate an “alternatively activated” phenotype in macrophages. We used high-density oligonucleotide microarrays to investigate the transcriptional profile induced in human monocytes by IL-13. After 8-h stimulation with IL-13, 142 genes were regulated …

The exploitation of the metagenome for novel biocatalysts by functional screening is determined by the ability to express the respective genes in a surrogate host. The probability of recovering a certain gene thereby depends on its abundance in the environmental DNA used for library construction, the …

On the basis of theoretical and empirical considerations the author concludes that values of chivalry, such as courtesy, politeness, etiquette, courage and honour are still relevant for the modern Cadets Corps. In particular rules of conduct, which find expression in etiquette, are the subject of investigation …

Muscle fiber-type specific expression of UCP3-protein is reported here for the firts time, using immunofluorescence microscopy

Dit boek is bedoeld voor analisten van objectgeoriënteerde systemen en degenen die hiervoor in opleiding zijn. Maar het boek kan ook interessant zijn voor wie zich bezig houdt met informatiemodellering in het algemeen. Dit boek beschrijft de EXPO-methode (expression based object modeling) waarmee op …

Recently, a role for uncoupling protein-3 (UCP3) in carbohydrate metabolism and in type 2 diabetes has been suggested. Mice overexpressing UCP3 in skeletal muscle showed reduced fasting plasma glucose levels, improved glucose tolerance after an oral glucose load, and reduced fasting plasma insulin levels. …