Accurate assessment of TP53 gene status in sporadic tumors and in the germline of individuals at high risk of cancer due to Li–Fraumeni Syndrome (LFS) has important clinical implications for diagnosis, surveillance, and therapy. Genomic data from more than 20,000 cancer genomes provide a wealth of information …

Musicians often play under circumstances in which pressure may lead to anxiety and performance deterioration. Theories suggest that a drop in performance is due to a shift in focus of attention towards task-irrelevant information. In this study, we asked music students to report what they think and where …

Objective The evaluation of voice quality is a major component of voice assessment. The aim of the present study was to develop a new multivariate acoustic model for the evaluation of breathiness. Method Concatenated voice samples of continuous speech and the sustained vowel [a:] from 970 subjects …

In this study, the construction of rumour on Twitter during a specific crisis is analysed from a discursive psychological perspective. This perspective treats psychological concepts such as identities as discursive constructions. The selected case is the robbery of a jewellery store in Deurne, a village …

Background: The modified painDETECT questionnaire (PDQ) is a self-reported questionnaire to discriminate between nociceptive and neuropathic-like pain in patients with knee/hip osteoarthritis (OA). This study aims to assess the structural and construct validity of this questionnaire. Methods: Confirmatory …

Rationale: Obesity is a risk factor for type 2 diabetes (DM2), however not all obese people develop DM2. We explored differences in energy intake and expenditure between obese older adults with and without DM2. Methods: Baseline data from 2 lifestyle interventions with a total of 202 obese older adults …

Purpose: The etiology of pain in osteoarthritis (OA) is complex and multifactorial. A growing number of studies suggest that modification of pain-transmission in the peripheral and central nervous system, leading to sensitization, plays a role in OA pain. Sensitization seems to be associated with neuropathic …

In this research report a port delay-analysis was created that showed the different ports where the Odin loaded and discharged. MV Odin is a general cargo ship which always sails in liner service. This means that MV Odin always loads and discharges in the same harbours. These harbours are in Oxelösund …

PURPOSE OF REVIEW: Protein delivery in the critically ill still is a highly debated issue. Here, we discuss only the most recent updates in the literature concerning protein nutrition of the critically ill. RECENT FINDINGS: Up to now, there are no randomized controlled trials (RCTs) published on enteral …