BACKGROUND: Since the benefit-harm balance of adding inhaled corticosteroids to long-acting β2-agonists (LABA) and long-acting muscarinic antagonists (LAMA) for patients with chronic obstructive pulmonary disease is unclear, we evaluated this addition for a range of patient profiles. METHODS: Analyses …

Since the start of the COVID-19 pandemic mental health problems among seafarers became more visible to the world. Seafarers seem to have some unhappy moments while working on board for several months. Especially during this pandemic life on board has been tougher than usual, shore leave is nearly impossible, …

Purpose: The study aims to explain the communicative basis of conflicts in which actors stand in opposition in defining a negotiated situation and to deepen knowledge of environmental conflict development, in particular on how frames are (re)shaped through discursive choices in interaction. Design/methodology/approach: This …

In immersive technology, digital (virtual) elements are added to the physical world. Immersion is the perception of being physically present in a non-physical world,or experiencing the physical presence of a non-physical element (like in Pokémon Go). Except that the first (fatal) accidents as a result …

The current study investigated how individual differences among children affect the added value of social robots for teaching second language (L2) vocabulary to young children. Specifically, we investigated the moderating role of three individual child characteristics deemed relevant for language learning: …

Purpose: The desirability of evaluating transition programs is widely acknowledged. This study aimed to explore the added value of transitional care investments for young adults with type 1 diabetes mellitus. Design and methods: Based on qualitative data, two groups of diabetes teams were created through …

Background: We developed an Internet-based physical activity (PA) support program (IPAS), which is embedded in a patient portal. We evaluated the effectiveness and costs of IPAS alone (online only) or IPAS combined with physiotherapist telephone counselling (blended care), compared to a control group. …

Airway care interventions may prevent accumulation of airway secretions and promote their evacuation, but evidence is scarce. Interventions include heated humidification, nebulization of mucolytics and/or bronchodilators, manual hyperinflation and use of mechanical insufflation-exsufflation (MI-E). Our …

Industrial, agricultural, and domestic sectors have an impact on the pollution of surface waters. More specifically, discharges of wastewater treatment plants also have a major impact on the quality of surface waters. According to PBL Netherlands Environmental Assessment Agency, Dutch surface waters …

The purpose of the model is to explore the influence of the design of circular business models (CBMs) on CBM viability. The model represents an Industrial Symbiosis Network (ISN) in which a processor uses the organic waste from suppliers to produce biogas and nutrient rich digestate for local reuse. …