The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation might be attributed to differences in angiotensin-1 …

A Bachelor Thesis on the Development of a Wool Seersucker Fabric using Differential Shrinkage

BACKGROUND: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an unpredictable pharmacokinetic/pharmacodynamic profile. Conventional intermittent …

BACKGROUND & AIMS: Oral supplementation with vitamin D is recommended for older adults to maintain a sufficient 25-hydroxyvitamin D (25(OH)D) status throughout the year. While supplementation with vitamin D2 or D3 is most common, alternative treatment regimens exist which require further investigation …

Background: Hypothyroidism is a common endocrine disorder and the standard treatment is replacement therapy with levothyroxine (LT4). Although many hypothyroid patients improve upon treatment with LT4, a proportion seems to experience residual hypothyroid complaints despite treatment, even when plasma …

Plasma gasification has been studied as a new technology which may combine bio-waste treatment and energy generation. Currently, a setup for carrying out gasification experiments has been built up in order to obtain more experimental data for further research. According to previous experimental results, …

Inleiding: Knie-artrose of gonartrose is een aandoening van het kniegewricht en wordt als een van de meest voorkomende oorzaken van invaliditeit genoemd. Startstijfheid in combinatie met pijn is kenmerkend echter, het is niet precies bekend waardoor pijn wordt veroorzaakt. Voor behandeling van gonartrose …

Dietary nitrate (NO3(-)) supplementation has been proposed as an emerging treatment strategy for type 2 diabetes. We hypothesized that ingestion of a single bolus of dietary NO3(-) ingestion improves oral glucose tolerance in patients with type 2 diabetes. Seventeen men with type 2 diabetes (glycated …

Inleiding: Fasciitis plantaris (FP) is één van de meest voorkomende pijnlijke aandoeningen aan de voet. Voor de behandelingen van FP zijn er in de loop de jaren talloze conservatieve en operatieve therapieën ontwikkeld. Bij ongeveer 10% van alle patiënten is een secundaire conservatieve therapie, zoals …

With a market demand for low cost, easy to produce, flexible and portable applications in healthcare, energy, biomedical or electronics markets, large research programs are initiated to develop new technologies to provide this demand with new innovative ideas. One of these fast developing technologies …