Background Gastrointestinal symptoms are common during chemotherapy, but underlying disturbances in gut function and their impact on daily life are unclear. This study investigates gut function in a heterogenous group of cancer patients with gastrointestinal symptoms during chemotherapy and its relation …

Increased intestinal permeability is linked to both intestinal as well as peripheral inflammatory disease. Contact between intestinal contents and the underlying immune system may account for excessive immune activation and local as well as systemic inflammation. Decreasing intestinal permeability using …

Microfluidic devices have the potential to adopt more accurate physiological conditions of the human intestine through the use of continuous flow and by producing mechanical stress to the cells. This study evaluated the translocation properties of a microfluidic gut-on-chip device in comparison with …

Exercise is one of the external factors associated with impairment of intestinal integrity, possibly leading to increased permeability and altered absorption. Here, we aimed to examine to what extent endurance exercise in the glycogen‐depleted state can affect intestinal permeability toward small molecules …